Leptospirosis can present with severe cases such as polymyositis, peripheral neuropathy, and rarely, Guillain-Barré Syndrome (GBS). This paper reports a case who presented dysarthria GBS. A female patient complaints of weakness, dizziness, diarrhea, dysarthric. Her assessments included muscle strength globally 4/5 deep tendon reflexes hypoactive. An electromyographic examination was performed t...

Background & Aims: Brucellosis is a public health problem in many developing countries, including Iran. Diagnosis is based on history, clinical manifestations and positive serum agglutination test (SAT) or Wright test. The purpose of this study was to evaluate the diagnostic value of SAT in pediatric Brucellosis. Methods: In this prospective study, during 2 years, 52 patients with clinical feat...

background: toxoplasma gondii can infect all warm-blooded animals. modified agglutination test (mat) and elisa are widely used for the detection of t. gondii antibodies. however, there is little information on their acceptability for detecting antibodies in companion animals. methods: this study compared elisa and mat for their ability to detect t. gondii infection in natu­rally infected dogs a...

Genes encoding lipoproteins LipL32, LipL41 and the outer-membrane protein OmpL1 of leptospira were recombined and cloned into a pVAX1 plasmid. BALB/c mice were immunized with LipL32 and recombined LipL32-41-OmpL1 using DNA-DNA, DNA-protein and protein-protein strategies, respectively. Prime immunization was on day 1, boost immunizations were on day 11 and day 21. Sera were collected from each m...

The performance of a direct agglutination test for the detection of toxoplasma specific IgG immunoglobulin was compared with that ofthe latex agglutination test. The direct agglutination test was less sensitive but more specific than the latex agglutination test. Quantitative results were not directly comparable, reflecting the different antibody profiles detected in each assay. The direct aggl...

Methods An ongoing prospective study conducted from June 2012October 2013 in 90 HIV seropositive patients presenting with various complaints. CSF and lymphnode aspirates were subjected to preliminary microscopic examination, c (Giemsa staining, mucicarmine staining, negative staining and Gram’s staining). Latex agglutination test was done for CSF samples. Sampls inoculated on SDA at 37C and 25C...

Experimental infection of marmoset monkeys (Callithrix jacchus) with Leptospira interrogans serovar Copenhageni showed microscopic patterns of tissue reactions comparable to those seen in the severe forms of human leptospirosis, including intra-alveolar hemorrhage. The most impressive microscopic changes were seen in the lung and kidney of animals killed at days 6 and 12 after inoculation. Ther...

OBJECTIVE To detect leptospiral antibodies by microscopic agglutination test (MAT) in north-east of Iran. METHODS This study was conducted to evaluate prevalence of human leptospiral infections by MAT, using six current reference strains of Leptospira interrogans in north-east of Iran. A total of 285 serum samples were collected from three north-east provinces of Iran, from December, 2009 to ...

Anti-D immunoglobulin; BioVue column agglutination test; Quality control; Haemolytic disease; Anti-Rh(D) titration; Rh-factor Abstract The preparation anti-D immunoglobulin is an important therapy for both treatment and protection. Titer of anti-D immunoglobulin preparation is an important factor to determine the dose of treatment. Many methods are used to evaluate the titer of anti-D immunoglo...