background: migraine is a chronic  neurological  disorder, characterized  by recurrent  moderate to severe headaches. worldwide migraine a=ects nearly 15%. studies suggest that genes involved in the production of nitric oxide (no) may act as genetic  factors for migraine. no synthase  3 (nos3) by expressing  enzyme nos regulates  endothelial  derived no. one  class of  medications   used  as  f...

BACKGROUND A migraine attack aggregates a range of different symptoms, besides pain, that contribute to attack-related disability. Cognitive dysfunction is an unacknowledged part of the migraine attack. OBJECTIVE To provide a profile of the frequency and character of migraine attack-related cognitive symptoms occurring during the headache phase of the attack. STUDY DESIGN Cross-sectional su...

The aim of the study was to perform a mapping and umbrella review with meta-meta-analysis (MMA) synthesise critically evaluate effectiveness manual therapy (MT) aerobic exercise (AE) in relation pain intensity, frequency, disability quality life patients migraines, tension-type headaches (TTH) cervicogenic (CGH). A systematic search conducted PubMed, PEDro, Scielo Google Scholar up December 202...

Migraine is currently conceptualized as a chronic disease with episodic manifestations, with attacks that increase in frequency in a subgroup (migraine transformation or progression). T ransformation of migraine may be subdivided in three partially overlapping forms, although research in this area is still in infancy, and evidence is sometimes weak Typically, transformation refers to increases ...

Chronic migraine is a disabling neurologic condition that affects 2% of the general population. Patients with chronic migraine have headaches on at least 15 days a month, with at least eight days a month on which their headaches and associated symptoms meet diagnostic criteria for migraine. Chronic migraine places an enormous burden on patients owing to frequent headaches; hypersensitivity to v...

INTRODUCTION Hemiplegic migraine is a particularly severe form of the disease that often evolves to a debilitating chronic illness that is resistant to commonly available therapies. Peripheral neurostimulation has been found to be a beneficial therapy for some patients among several diagnostic classes of migraine, but its potential has not been specifically evaluated for hemiplegic migraine. ...

background : a wide range of preventive medications for migraine attacks, with varying efficacy is currently in use. studies comparing the efficacies of these drugs would be of value in the proper treatment of the disease. the present study compared the frequency, duration and intensity of migraine attacks during and following treatment with cyproheptadine (4 mg, twice daily) or blellergal (bel...

background: the sporadic type of hemiplegic migraine (hm) is sometimes observed among migrainous patients (mp) and mimics ischemic strokes. methods: in an evaluation of two-hundred consecutive adult mp in the mackenzie headache clinic, canada during 2004 , 9% of the patients met the criteria established by the international headache society for sporadic hm. female to male sex ratio, family hist...

BACKGROUND Some migraine patients find that regular exercise helps in reducing the frequency of headache attacks. In addition, exercise in migraine is recommended from many headache experts. However, most of these recommendations refer to some anecdotal reports or observational studies in literature stating that regular exercise can reduce the frequency and severity of migraine. OBJECTIVE The...