The glycopeptide vancomycin has an antimicrobial effect by halting the synthesis of bacterial cell-wall binding D-Ala-D-Ala peptide motif precursor Lipid II. This interaction been extensively investigated using techniques such as XRD and NMR. Here, complexed with Ala-γGlu-Lys-D-Ala-D-Ala (the pentapeptide part II) is studied means Raman optical activity (ROA) spectroscopy. Where for conventiona...

The delta-amino acid 5-aminolevulinic (ALA), is the precursor of endogenous photosensitiser Protoporphyrin IX (PpIX), and currently approved for Photodynamic Therapy (PDT) certain superficial cancers. However, ALA-PDT not very effective in diseases which T-cells play a significant role. Cutaneous T-cell lymphomas (CTCL) group non-Hodgkin malignant diseases, includes mycosis fungoides (MF) Sézar...

introduction: the use of lopinavir/ritonavir (lpv/r) has decreased morbidity and mortality due to human immunodeficiency virus (hiv); however its use could be impaired by hepatotoxicity. therefore, this study was designed to investigate the effects of melatonin (mt) and alpha lipoic acid (ala) on lpv/r-induced hepatotoxicity in male albino rats. methods: rats were divided into groups and treate...

introduction: this study evaluated the effects of pretreatments with melatonin (mt), and alpha lipoic acid (ala) on lopinavir/ritonavir (lpv/r) -induced serum levels of creatinine (cr), urea (u), uric acid (ua) and kidney levels of malondialdehyde (mda), superoxide dismutase (sod), glutathione (gsh) and catalase (cat) in male albino rats. effects of treatments with mt and ala were also evaluate...

We introduce the cyclic major index of a permutation and give bivariate analogue enumerative formula for shuffles with given descent number due to Adin, Gessel, Reiner Roichman, which can be viewed as Stanley's shuffling theorem. This gives an answer question has been posed by Domagalski, Liang, Minnich, Sagan, Schmidt Sietsema again.

mirza abdollah afandi, the son of mirza eisa was one of the most famous authors and scholars in 11th and 12th century. someone has named he tabrizi, jeirani, esfahani and … he was a tourist in a half of his life time and in addition to iran cities, he had traveled to rome, turkey, syria, egypt, arabia, bahrain and … he observed libraries of those countries and profited the knowledge of the scho...

background: photodynamic therapy (pdt) is a promising therapeutic modality for the treatment of cancer and other diseases. in this study, the epidermoid carcinoma cell line a431 and the normal fibroblasts were used to investigate whether gold nanoparticles (gnps) can induce an increase in cell death during pdt using 5-aminolevulinic acid (5-ala) as a photosensitizer. methods: human fibroblast a...