BACKGROUND Array CGH is the criterion standard for identifying copy number variations (CNV), but the restrictive requirement of DNA quality and relatively high cost prevent the use of this method as a general assay in hospitals in developing countries. Our principal objective was to determine whether the semiconductor sequencing platform (SSP) could be an alternative method in CNV detection for...

Presentation A 32-year-old woman developed severe recurrent hypoglycemia after a medically assisted, first-trimester abortion. She had had type 1 diabetes since 1988, and the pregnancy was her first and planned. The patient’s glycemic control had been good, with a preconception A1C of 6.3%. She was on a multiple daily injection insulin regimen and routinely counted carbohydrate. Unfortunately, ...

OBJECTIVE The objective of the study was to explore the experiences of those who have experienced miscarriage, focusing on men's and women's accounts of miscarriage. DESIGN This was a qualitative study using a phenomenological framework. Following in-depth semistructured interviews, analysis was undertaken in order to identify superordinate themes relating to their experience of miscarriage. ...

INTRODUCTION International Classification of Disease, Ninth Revision (ICD-9) diagnosis codes have not been validated for identifying cases of missed abortion where a pregnancy is no longer viable but the cervical os remains closed. Our goal was to assess whether ICD-9 code "632" for missed abortion has high sensitivity and positive predictive value (PPV) in identifying patients in the emergency...

Results differ as to whether Brucella infection during pregnancy increases a woman's risk of miscarriage. We determined the seroprevalence of BrucelIa spp. among a sample of women with miscarriage and women with no history of miscarriage in Jordan during January-July 2003. Serum samples were collected from 445 women with miscarriage and a similar number of women with no history of miscarriage, ...

A 31-year-old lady presented with abnormal vaginal bleeding during her first trimester of pregnancy. Based on the ultrasound findings and decreasing hCG trend (from 1040 mIU/mL to 759 mIU/mL), a diagnosis missed miscarriage was made. week later, patient heavy bleeding. Ultrasound showed classic snowstorm appearance suggestive complete hydatidiform mole. The serum level however, 357 mIU/mL. In c...

Many readers will be surprised to learn that antenatal betamethasone is not licensed by the UK Medicines and Healthcare products Regulatory Agency (MHRA, formally the Medicines Control Agency) to prevent neonatal respiratory distress syndrome in pregnancy. Nor is oxytocin 10 units im licensed to prevent postpartum haemorrhage. However, oxytocin 5 units iv is licensed to treat a missed miscarria...

Yan Fang1, Beihua Kong1,5, Qifeng Yang2, Daoxin Ma3, and Xun Qu4 Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, 107 Wenhuaxi Road, Ji’nan 250012, Shandong, People’s Republic of China Department of General Surgery, Qilu Hospital, Shandong University, Ji’nan, Shandong, People’s Republic of China Department of Hematology, Qilu Hospital, Shandong University, Ji’nan, Sh...