Hemodynamic deterioration because of worsening of mitral regurgitation can occur in a small number of patients undergoing atrioventricular node (AVN) ablation and pacing therapy. Patients with moderate mitral regurgitation before ablation seem prone to this complication. Successful permanent His-bundle pacing after AVN ablation was performed in a patient with chronic atrial fibrillation and mod...

Mitral regurgitation due to papillary muscle rupture after blunt chest trauma is uncommon. Sudden onset severe mitral regurgitation may lead to death due to heart failure if surgical repair is delayed. A previously healthy 12-year-old girl underwent splenectomy and chest tube insertion for pneumothorax after a traffic accident in a vehicle 15 days before. She was discharged from the hospital af...

We evaluated 147 patients with adequate color Doppler and angiographic studies for mitral regurgitation. Sixty-five patients had no mitral regurgitation by both color Doppler and angiography and 82 patients had mitral regurgitation by both techniques. Thus the sensitivity and specificity of color Doppler for the detection of mitral regurgitation was 100%. Three two-dimensional echocardiographic...

Background. The ability of transesophageal color Doppler echocardiography to provide high-resolution images of both cardiac structure and blood flow in real time is advantageous for many clinical purposes. This study was performed to determine the utility of the regurgitant jet width at its origin measured by transesophageal Doppler color flow imaging in the assessment of severity of mitral reg...

Percutaneous mitral balloon valvotomy (PMV) has evolved into an effective method for the treatment of patients with symptomatic mitral stenosis. An increase in mitral regurgitation can occur in '45% of patients undergoing PMV. Severe mitral regurgitation can be caused by rupture of chordae or of a papillary muscle. Noncommissural tearing of the mitral leaflet is also an important mechanism of s...

This study tested whether the modest hypertrophy that develops in dogs in response to mitral regurgitation is due to a relatively small change in the rate of protein synthesis or, alternatively, is due to a decreased rate of protein degradation. After 3 mo of severe experimental mitral regurgitation, the left ventricular (LV) mass-to-body weight ratio increased by 23% compared with baseline val...

BACKGROUND Ischemic mitral regurgitation often complicates severe ischemic heart disease and adversely affects the prognosis in these patients. There is wide variation in the clinical spectrum of ischemic mitral regurgitation due to varying location and chronicity of ischemia and anomalies in annular and ventricular remodeling. As a result, there is lack of consensus in treating these patients....

T he hammock mitral valve is a rare congenital abnormality resulting in mitral stenosis, mitral regurgitation, or both. Although sometimes technically challenging, the repair of such lesion is possible and should be preferred to mitral valve replacement. We describe here for the first time the case of an adult patient who underwent mitral valve repair for severe mitral regurgitation related to ...

In this issue of Circulation, Bursi et al 1 report that ischemic mitral regurgitation is a more common finding after myocardial infarction (MI) than was previously thought and is an independent predictor of heart failure and death among 30-day infarct survivors. Seldom is mitral regurgitation actively investigated, and investigation is often only prompted by clinical examination. The data Bursi...

Since the initial description of mitral valve prolapse as billowing mitral leaflets leading to regurgitation (1-4), physicians have had to contend with the problem of its noninvasive diagnosis (5-9). Lack of specificity of diagnostic criteria led to a "disease by definition" frequently diagnosed in otherwise normal subjects (10-22). Recent efforts have attempted to restore prolapse to the categ...