A series of observations on the blood of patients acutely ill with scarlet fever has shown that a toxic substance can be demonstrated in the serum by means of intracutaneous injections of the serum in persons who have not had scarlet fever and whose serums fail to blanch the rash in scarlet fever. The reaction caused by this substance consists of a bright red local erythema, varying from 20 to ...

As part of a study of protein and peptide metabolism lysine was synthesized with Cl4 in the e position and resolved into the L and D isomers. 10 mg. of labeled lysine dihydrochloride (either Lor D-) and 0.66 gm. (wet weight) of guinea pig liver homogenate were added to a reaction mixture containing 1.3 per cent of an amino acid mixture corresponding to the composition of casein except for lysin...

The presented study aimed at the evaluation of hydrochlorothiazide influence on cilazapril stability in model mixture and fixed dose tablet formulation. The degradation of cilazapril in the presence of hydrochlorothiazide took place according to autocatalytic reaction kinetic mechanism, described mathematically by Prout-Tompkins equation. Hydrochlorothiazide coexistence with cilazapril in model...

Room-temperature vulcanizing silicone and homopolymers of 2-hydroxyethyl methacrylate (HEMA) have been used to permanently inflate detachable balloons [1] . HEMA is preferred over silicone because it is less viscous and is water soluble. Goto et al. [2] described a commercially available (HEMA A, lnterventional Therapeutics, S. San Francisco, CA) polymerizing substance that includes HEMA as the...

Overview Neurologists and primary care doctors manage patients with a wide range of psychiatric disturbances to include personality disorders. The definition of a personality disorder encompasses individuals with interpersonal or psychosocial dysfunction that impairs their social or professional function. Personality disorders are common in the general population occurring in 1-2% of the adult ...

Vasospasm of the basilar artery in 57 cats was induced by application of fresh blood, or a blood and cerebrospinal fluid (CSF) mixture incubated at 37 degrees C for 2 to 16 days. In animals treated with fresh blood or mixtures incubated for over 15 days, the severity of induced vasoconstriction is slight and duration short. Mixtures incubated 5 to 10 days induced severe and prolonged vasoconstr...

Streptomyces antibioticus synthesizes a mixture of actinomycins (I to V), each of which possesses 2 moles of n-valine per mole of antibiotic (1, 2) ; occasionally a sixth substance is produced in trace amounts. Streptomyces chrysomallus, on the other hand, forms a mixture consisting of actinomycins IV (containing 2 moles of n-valine), VI (containing 1 mole of n-valine and 1 mole of n-alloisoleu...

Missing data is a pervasive problem in longitudinal treatment research studies. Missing data due to study non-completion complicate the task of drawing conclusions about the effect of a treatment or policy on a measure of interest (e.g., a process measure or outcome). Biased estimates of change over time in a measure could result if attrition is related to the constructs that are being measured...