BACKGROUND Supportive supervision has been found to be more effective than corrective fault-oriented inspections. Uganda's Ministry of Health in 2012 implemented a comprehensive strategy (SPARS) to build medicines management capacity in public sector health facilities. The approach includes supportive supervision. This structured observational study assesses supportive supervision competency am...

It is widely accepted that atmospheric pO2 < 1 ppm before the Great Oxidation Event. Yet a recent study found fossil micrometeorites (MMs) containing oxidized iron species wüstite (FeO) and magnetite (Fe3O4) formed 2.7 billion years ago (Ga). How these MMs became uncertain. Abundant O2 in upper atmosphere oxidation by CO2 have been suggested. However, photochemical reactions cannot produce suff...

The c-jun proto-oncogene plays a vital role in the carcinogenic process. Although numerous works have extensively investigated the induction mechanisms of c-jun by UV, hydrogen peroxide or 12-O-tetradecanoylphorbol-13-acetate, the mechanism induced by alkylating agents has received little attention. In this study, NIH 3T3 cells were exposed to methylmethanesulfonate (MMS), revealing that the ag...

MMS provides multimedia messaging solution to contemporary and evolving wireless communications. Both SMS and Email have been widely used for messaging in wireless and fixed networks respectively, but none of these is capable enough to fulfill the present and the future demands of wireless messaging. None of the existing messaging systems can also take full advantages of the recent technologica...

Previously, we have shown that paraspeckle protein 1 (PSPC1), a protein component of paraspeckles that was involved in cisplatin-induced DNA damage response (DDR), probably functions at the G1/S checkpoint. In the current study, we further examined the role of PSPC1 in another DNA-damaging agent, methyl methanesulfonate (MMS)-induced DDR, in particular, focusing on MMS-induced apoptosis in HeLa...

BACKGROUND Extramammary Paget disease (EMPD) is a rare intraepithelial neoplasm of the skin characterized by ill-defined margins and high recurrence rates after wide local excision. Although Mohs micrographic surgery (MMS) has been proposed to decrease the rate of local recurrence, the efficacy of MMS for this condition has not yet been established. OBJECTIVE We sought to assess the efficacy ...

Man-made marine structures (MMS) are commonly used to describe any artificial structure in the environment, encompassing oil and gas infrastructure pipelines, reefs, jetties, piers shipwrecks. MMS increasingly proposed address issues facing planners, including augmenting fish stocks through creation of reefs repurposing redundant offshore (‘rigs reefs’). Marine spatial planning is a highly cont...

We suggest that if the astrophysical site for r-process nucleosynthesis in the early Galaxy is confined to a narrow mass range of Type II supernova (SN II) progenitors, with a lower mass limit of Mms=20 M middle dot in circle, a unique feature in the observed distribution of [Ba/Mg] versus [Mg/H] for extremely metal-poor stars can be adequately reproduced. We associate this feature, a bifurcati...

The need for higher capacity battery cells has increased significantly during the past years. Therefore, subject of this study is to investigate behavior high performance 21700 Lithium-Ion cylindric under several abuse conditions, represented by mechanical loads with different velocities and states charge (SoC), develop a finite element analysis (FEA) model, using OpenRadioss’ explicit solver c...

The fairness notion of maximin share (MMS) guarantee underlies a deployed algorithm for allocating indivisible goods under additive valuations. Our goal is to understand when we can expect to be able to give each player his MMS guarantee. Previous work has shown that such an MMS allocation may not exist, but the counterexample requires a number of goods that is exponential in the number of play...