background: the use of assisted reproductive technology (art) is increasing in the world. the rate, efficacy and safety of art are very different among countries. there is an increase in the use of intra cytoplasmic sperm injection (icsi), single fresh embryo transfer (et) and frozen-thawed embryo transfer (fet). objective: the objective of this study was to compare pregnancy rate in fresh et a...

Background and Objective: In- vitro fertilization (IVF) is one of the approved treatment options for infertility. Despite many progresses in this field, its success rate is about 20 -25%. Utilization of drugs which suppress or decrease uterine smooth muscle contraction before embryo transfer, theoretically can improve fertility by increasing implantation rate. This study was designed to evaluat...

background: recurrent implantation failure is one of the most issues in ivf cycles.some researchers found that beneficial effects of endometrial scratching in womenwith recurrent implantation failure, while some authors demonstrated contrary resultsobjective: the present study aimed to investigate the effect of intrauterine. salineinfusion as a form of endometrial injury, during fresh in vitro ...

Objective Women undergoing IVF cycles should go successfully through multiple points during the procedure (i.e., implantation, clinical pregnancy, no spontaneous abortion and delivery) to achieve live births. On the other there is a need to consider previous reproductive outcomes and as well as the current cycle. In this study, data on multiple cycles and multiple points during the IVF cycle ar...

BACKGROUND The use of ultrasound-guided embryo transfer has been reported to affect success rates in some centres but not others. In a prospective study, we examined the influence of ultrasound guidance in embryo transfer performed on different days after oocyte retrieval. METHODS Two different methods of embryo transfer were evaluated in 1069 consecutive transfers. The ultrasound-guided embr...

BACKGROUND It has become an accepted procedure to transfer more than one embryo to the patient to achieve acceptable ongoing pregnancy rates. However, transfers of more than a single embryo increase the probability of establishing a multiple gestation. Single-embryo transfer can minimize twin pregnancies but may also lower live birth rates. This meta-analysis aimed to compare current data on si...

BACKGROUND/AIMS Catheter injection speed affects depth and placement of the embryo into the uterine cavity and is shown to be highly variable in, and between, subjects in a manually performed embryo transfer. In an effort to standardize the injection speed during embryo transfer, we developed an automated transfer pump: the pump-regulated embryo transfer (PRET) device. In this randomized contro...

Trophinin is a membrane protein that is potentially involved in human embryo implantation by mediating homophillic cell adhesion between trophoblastic cells and endometrial cells. Trophinin expression by maternal cells may be induced by the embryo that secretes human chorionic gonadotropin (hCG). Because the process of tumor metastasis resembles that of trophoblast invasion and proliferation du...