Panthenol is the alcohol analogue of panthothenic acid, known as vitamin B5, which is required for the biosynthesis of coenzyme A in cells. This compound exists as two stereoisomers, D-pathenol and L-panthenol, only the former being biologically active (1). It is a common ingredient in pharmaceutical products, for example in topical treatments for rhinitis, conjunctivitis, sunburn, and wounds, ...

risk of developing melanoma, even after skin cancer risk factors including skin type are controlled for. Hispanics also are less knowledgeable about melanoma, less likely to perform self-examinations, and often unaware of the clinical signs of skin cancer; they have worse outcomes. The worse outcomes are to result from issues of health care delivery, but the possibility exists that melanomas in...

On the other hand, an increase in environmental humidity also induced abnormalities in permeability homeostasis [9] . In this issue of Exogenous Dermatology, environmental factors on dry skin are discussed by fi ve distinguished experts (or their groups) in this fi eld: Wertz (this issue) gives an integrated overview of the epidermal barrier function and their regional variations. His contribut...

Herbal cosmetics are gaining popularity over chemicals for beauty products. However, natural products often prone to deterioration. Therefore, stability and compatibility testing the main examinations of safety reliability herbal cosmetics. Liquid crystal structures provide better application performances than conventional emulsion systems in terms stability, controlled release, moisturizing. R...

Filaggrin is a structural protein that aggregate keratin filament and form cornified envelope which strengthen corneocytes. Also, filaggrin are degraded into natural moisturizing factor (NMF) which helps keeping stratum corneum hydrated and maintain acidic skin pH. The component of NMF is including sodium pyrrolidone carboxylic acid (PCA), urocanic acid, alanine, lactate and urea [2,3]. Mutatio...

The pH of the skin is slightly acidic (4.6 to 5.8) which is important for appropriate antibacterial, antifungal, constitution of barrier function, as well as structuring and maturation of the stratum corneum. This study aimed to evaluate the pH of the main commercial moisturizers and liquid soaps in Brazil. Thus, pH of the products was quantified by pH meter in three measurements. A total of 38...