Non-covalent molecular imprinting of poly(allylamine hydrochloride) (PAA HCl) with glucose phosphate mono-sodium salt produced molecularly imprinted polymer (MIP) hydrogels capable of quantitative, isomerically specific binding of glucose. By ionic association of a template molecule, glucose phosphate mono-sodium salt, to the polymer prior to covalent crosslinking, MIP hydrogels were created wi...

Molecular imprinting is a technique used to synthesize polymers that display selective recognition for a given molecule of interest. In this study, the role of hydrogel electrostatic charge density on the recognition and selectivity properties of protein-imprinted hydrogels was explored, and the effect of variations of the template extraction protocol on the MIP recognition properties were also...

The cover picture shows the electrochemical detection of dihydroxy benzene by nano-electrocatalysts based on carbonaceous nanomaterials (i.e., carbon nanotubes, graphene, and their derivatives) non-carbonaceous metal-organic frameworks, molecular imprinted polymers, other nanomaterials). See Reviews Part 1 (DOI:10.1002/tcr.202100043) 2 (DOI:10.1002/tcr.202100044) Md. Abdul Aziz, A. J. Saleh Aha...

Solid phase extraction is one of the major applications of molecularly imprinted polymers fields for clean-up of environmental and biological samples namely molecularly imprinted solid-phase extraction. In this study, solid phase extraction using the imprinted polymer has been optimized with the experimental design approach for a triazine herbicide, named atrazine with regard to the critical fa...

The aim of this work was to investigate the possibility of employing semi-covalent molecularly imprinted polymers (MIPs) as a controlled release device for ibuprofen and naproxen in biological fluids, especially gastrointestinal ones, compared to non imprinted polymers (NIPs). The carboxyl groups of ibuprofen and naproxen were converted to vinyl ester group by reacting ibuprofen and vinyl aceta...

A series of fluorescent molecularly imprinted polymers has been prepared with a view to generating material capable of mimicking the binding characteristics of the metabolically important cytochrome isoform CYP2D6. Such polymers would have the possibility to form the sensing element in a high-throughput assay for the prediction of CYP2D6 affinity. The imprinted polymers possessed binding-depend...

Mechanisms of interaction of a three-dimensional polymer with solutes are of interest in the development and function of synthetic biomimetic polymers. We have investigated the effects of template/monomer interactions and template concentration on conversion and polymerization rates of a molecularly imprinted polymer. Copolymers of 2-hydroxyethyl methacrylate (HEMA) and poly(ethylene glycol) di...

Molecular Imprinted Polymers (MIPs) have been used for recognition and binding of different compounds. We are developing MIPs to selectively bind organophosphate pesticides and toxic chemical warfare nerve agents. MIPs were made to the pesticide Dichlorvos. Control MIPs were made without the template. Dichlorvos-MIPs bound more Dichlorvos in comparison to control-MIPs. The Dichlorvos-MIPs can b...