background: despite many efforts, the etiology of autism remains unknown. food allergy has been suggested as a pathogenic factor in autism spectrum disorder (asd). our aim in this study was to determine whether food allergy could be considered as a risk factor for autistic children. methods: thirty-nine autistic children were examined by the skin prick test (spt), and total serum ige was evalua...

Many families are directly involved in caring of their children with the lifelong autistic spectrum disorders. Sometimes, they are the victims of their children's behaviors. The family, including siblings, may have to explain the children's behaviors to others. Their mothers have poorer mental health with difficulties in family adaptability and cohesion. Its burden is not just limited to psycho...

sleep disorders in children can lead to considerable complications. in some mental disorders including autism, it has more importance. despite the importance of sleep in children developments and lives, few researches have conducted in this area therefore this research is going to investigate sleep behavioral disorders in children and compare with normal children. research design was causal-com...

OBJECTIVE Transient gestational hypothyroxinemia in rodents induces cortical neuronal migration brain lesions resembling those of autism. We investigated the association between maternal hypothyroxinemia (gestational weeks 6-18) and autistic symptoms in children. METHODS The mother-and-child cohort of the Generation R Study (Rotterdam, the Netherlands) began prenatal enrollment between 2002 a...

BACKGROUND The etiology of autism is complex, and may involve the interaction between genetic and environmental factors. Recent studies suggested an association between maternal immune response and this disorder. METHODS Forty-nine women with autistic children (cases) were studied in comparison with 73 women with normal children (controls). After interviewing for sociodemographic and clinical...

Objective: To explore the perceived burden and stress among mothers of autistic children. Methods: This cross-sectional study was conducted at Riphah International University over a period of 4 months from October, 2020 to January, 2021. Sample was recruited using non-probability convenience sampling and comprised of N=84, 23- 60 years old mothers of children aged 3-16 years with autism spectr...

Several recent lines of inquiry have pointed to the amygdala as a potential lesion site in autism. Because one function of the amygdala may be to produce autonomic arousal at the sight of a significant face, we compared the responses of autistic children to their mothers' face and to a plain paper cup. Unlike normals, the autistic children as a whole did not show a larger response to the person...

BACKGROUND The Autism Spectrum Quotient (AQ) is a self-report questionnaire for quantifying autistic traits. This study tests whether the AQ can differentiate between parents of children with an autism spectrum condition (ASC) and control parents. In this paper, the use of the AQ to define the broader, medium and narrow autism phenotypes (BAP, MAP, NAP) is reported, and the proportion of parent...

BACKGROUND Parents of children with autism have higher rates of broad autism phenotype (BAP) features than parents of typically developing children (TDC) in Western countries. This study was designed to examine the rate of BAP features in parents of children with autism and the relationship between parental BAP and the social impairment of their children in a Chinese sample. METHODS A total o...