The convergence of social networking andmobile computing is expected to generate a new class of applications, called Mobile Social Networking (MSN) applications, that will be of significant importance for the coming years. Indeed,MSN enhances the capabilities ofmore traditional Online Social Networking (OSN) to a great extent by enabling mobile users to benefit from opportunistically created so...

OBJECTIVES The Internet provides great opportunities for patient healthcare education, but poses risks that inaccurate, outdated or harmful information will be disseminated. Our objective was determine the quality of the information available on the internet in relation to oral leukoplakia. STUDY DESIGN Sites were identified using 3 search engines (Google, Yahoo and MSN), and the search term ...

The Drosophila misshapen (msn) gene is a member of the STE20 kinase family. We show that msn acts in the Frizzled (Fz) mediated epithelial planar polarity (EPP) signaling pathway in eyes and wings. Both msn loss- and gain-of-function result in defective ommatidial polarity and wing hair formation. Genetic and biochemical analyses indicate that msn acts downstream of fz and dishevelled (dsh) in ...

To determine the optimal treatment margin of local ablation therapy for small hepatocellular carcinoma (HCC), we investigated characteristics of microscopic satellite HCC nodules (msn) using resected livers, and the incidence of local recurrences in patients who underwent percutaneous microwave coagulation therapy (PMCT) according to whether or not an adequate treatment margin was achieved. We ...

Multidrug resistance (MDR) is the major clinical obstacle in the management of cancer by chemotherapy. Overexpression of ATP-dependent efflux transporter P-glycoprotein (PGP) is a key factor contributing to multidrug resistance of cancer cells. The purpose of the present study was to use the endosomal pH-sensitive MSN (mesoporous silica nanoparticles; MSN-Hydrazone-Dox) for controlled release o...

A multi-functional mesoporous silica nanoparticle (MSN)-based boron neutron capture therapy (BNCT) agent, designated as T-Gal-B-Cy3@MSN, was synthesized with hydrophobic mesopores for incorporating a large amount of o-carborane (almost 60% (w/w) boron atoms per MSN), and the amines on the external surface were conjugated with trivalent galactosyl ligands and fluorescent dyes for cell targeting ...

This eye-opener article aims at introducing the health GIS community to the emerging online consumer geoinformatics services from Google and Microsoft (MSN), and their potential utility in creating custom online interactive health maps. Using the programmable interfaces provided by Google and MSN, we created three interactive demonstrator maps of England's Strategic Health Authorities. These ca...

BACKGROUND Substance use disorders are a major public health problem. As primary care providers, nurse practitioners (NPs) must be proficient at screening, identifying, and intervening for at-risk patients. Screening, brief intervention, and referral to treatment (SBIRT) is a well-established, evidence-based model for teaching behavioral health skills to health care providers. It is vital that ...