نتایج جستجو برای: msra
تعداد نتایج: 346 فیلتر نتایج به سال:
Two types of methionine (Met) sulfoxide reductases (Msr) catalyze the reduction of Met sulfoxide (MetSO) back to Met. MsrA, well characterized in plants, exhibits an activity restricted to the Met-S-SO-enantiomer. Recently, a new type of Msr enzyme, called MsrB, has been identified in various organisms and shown to catalytically reduce the R-enantiomer of MetSO. In plants, very little informati...
Background and Objectives Macrolide, lincosamide and streptogramin B (MLS B) are noteworthy antibiotics for the treatment of Staphylococcus aureus infections. The purpose of this study, was to determine the phenotypic and genotypic characterization of macrolide resistance, among S. aureus, isolated from clinical samples and nasal swabs. Materials and Methods Totally, 162 non-duplicate S. aure...
We report an experiment in which a highperformance boosting based NER model originally designed for multiple European languages is instead applied to the Chinese named entity recognition task of the third SIGHAN Chinese language processing bakeoff. Using a simple characterbased model along with a set of features that are easily obtained from the Chinese input strings, the system described emplo...
Calcium/calmodulin (Ca2+/CaM)-dependent protein kinase II (CaMKII) couples increases in cellular Ca2+ to fundamental responses in excitable cells. CaMKII was identified over 20 years ago by activation dependence on Ca2+/CaM, but recent evidence shows that CaMKII activity is also enhanced by pro-oxidant conditions. Here we show that oxidation of paired regulatory domain methionine residues susta...
In this paper, we report the joint participation of I2R-NUS team and MSRA team in entity linking task for Knowledge Base Population at Text Analysis Conference 2011. I2R-NUS team submitted two results with the full system and the partial system for diagnosis purpose. Both results incorporate the new technologies: acronym expansion, instance selection and topic modeling proposed in our recent pa...
Progress identifying the genetic determinants of personality has historically been slow, with candidate gene studies and small-scale genome-wide association studies yielding few reproducible results. In the UK Biobank study, genetic variants in CADM2 and MSRA were recently shown to influence risk taking behavior and irritability respectively, representing some of the first genomic loci to be as...
This paper presents the Chinese word segmentation systems developed by Speech and Hearing Research Group of National Laboratory on Machine Perception (NLMP) at Peking University, which were evaluated in the third International Chinese Word Segmentation Bakeoff held by SIGHAN. The Chinese character-based maximum entropy model, which switches the word segmentation task to a classification task, i...
Visceral obesity is linked to insulin resistance and cardiovascular disease. A recent genetic study indicated that the gene locus for the anti-oxidant defense enzyme methionine sulphoxide reductase A (MsrA) is positively associated with the development of visceral adiposity. This work tested the hypothesis that Msr activity is diminished in visceral fat as a result of obesity. It used two anima...
In a recent study on the reducing requirement for the methionine sulfoxide reductases (Msr) (Sagher, D., Brunell, D., Hejtmancik, J. F., Kantorow, M., Brot, N. & Weissbach, H. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 8656-8661), we have shown that thioredoxin, although an excellent reducing system for Escherichia coli MsrA and MsrB and bovine MsrA, is not an efficient reducing agent for eith...
We evaluate our method (LEGS) on four benchmark data sets (MSRA-5000 [7], SOD [9], ECCSD [10] and PASCALS [6]) against ten state-of-the-art models (SVO [1], PCA [8], DRFI [3], GC [2], HS [10], MR [11], UFO [4], wCtr [12], CPMC-GBVS [6] and HDCT [5]). We use either the implementations or the saliency maps provided by the authors for fair comparison. Since the DRFI method is also trained on the M...
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