Domulti-level selection explanations of the evolutionof social traits deepen the understanding provided by single-level explanations? Central tomultilevel explanations is a mathematical theorem, the multi-level Price decomposition. I build a framework through which to understand the explanatory role of such non-empirical decompositions in scienti c practice. Applying this general framework to t...

We present a simple stochastic rule-based approach to multilevel modelling for computational systems biology. Populations are modelled using multilevel multisets; these contain both species and agents, with the latter possibly containing further such multisets. Rules are pairs of such multisets, but now allowing variables to occur (as well as species and agents), together with an associated sto...

BACKGROUND Primary care is being encouraged to implement multiprofessional, system level, chronic illness management approaches to depression. We undertook this study to identify and assess the quality of RCTs testing system level depression management interventions in primary care and to determine whether these interventions improve recovery. METHOD Searches of Medline and Cochrane Controlle...

BACKGROUND The uptake of guideline recommendations that improve heart failure (HF) outcomes remains suboptimal. We reviewed implementation interventions that improve physician adherence to these recommendations, and identified contextual factors associated with implementation success. METHODS We searched databases from January 1990 to November 2017 for studies testing interventions to improve...

BACKGROUND The RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework is a reliable tool for the translation of research to practice. This framework has been widely applied to assess the impact of individual interventions. However, RE-AIM has rarely been used to evaluate implementation interventions, especially from multi-sector partnerships. The primary purpose of t...

The occupational health area is developing models with a variety of methods to address and prevent job stress at the organization-level. A review of literature on employee assistance program (EAP) was conducted to explore relevant methods from its perspective. Result reveals that EAP is a potential good partner in the efforts to prevent Job stress at organization-level. Keywords-job stress; str...

The Food and Agriculture Organization of the United Nations promotes nutrition interventions considering food as the basis for action, given the strategic role of food and the agricultural sector to improve food security for the community; thus, a large number of people, especially the poor, who participate directly or indirectly in agricultural activities are able to obtain benefits from its m...

BACKGROUND Frailty is an aging syndrome caused by exceeding a threshold of decline across multiple organ systems leading to a decreased resistance to stressors. Treatment for frailty focuses on multi-domain interventions to target multiple affected functions in order to decrease the adverse outcomes of frailty. No systematic reviews on the effectiveness of multi-domain interventions exist in a ...