Little information is available regarding the duration of immunity achieved by Leptospira vaccination. The aim of this study was to assess in dogs the one-year protection induced by a leptospirosis vaccine against a Leptospira (L.) interrogans serovar icterohaemorrhagiae challenge. Six 8-9 week old dogs were immunised twice at a 3-week interval with a bivalent vaccine composed of inactivated ba...

ABSTRACT: Porcine circovirus 2 (PCV2) has a considerable economic impact on the pork industry worldwide for more than two decades. In 2016, new circovirus, porcine 3 (PCV3), was described; since then, it been reported to be associated with diseased or even in clinically healthy swine several countries. Considering importance of wild boars as reservoirs pathogens and extensive distribution these...

Granulomatous interstitial nephritis (GIN) is a rare entity detected in ∼0.5-0.9% of all renal biopsies. GIN has been linked to several antibiotics such as cephalosporins, vancomycin, nitrofurantoin and ciprofloxacin. It is also associated with NSAIDs and granulomatous disorders such as sarcoidosis, tuberculosis, fungal infections, and granulomatosis with polyangiitis. Renal biopsy is critical ...

Tiffany Shao, Jordan Weinstein, Serge Jothy and Marc Goldstein Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Division of Nephrology, Department of Medicine, St. Michael’s Hospital, Toronto, Ontario, Canada; and Department of Laboratory Medicine, St. Michael’s Hospital,...

5-Aminosalicylic acid (5-ASA) has structural similarities to both phenacetin and aspirin, which are known to cause 'analgesic nephropathy'. Because of the increasing use of 5-ASA, this paper draws attention to two cases of severe interstitial nephritis resulting from 5-ASA and emphasises the importance of monitoring renal functions of patients with inflammatory bowel diseases who are receiving ...

This study investigated the relationship between urinary protein excretion in lupus nephritis New Zealand black mice and renal pathology. A total of 328 lupus nephritis New Zealand black mice were established by a backcross hybridization method, and renal pathology was determined. The urinary protein excretion of the backcross mice over 24 h was compared and analyzed. Urinary protein excretion ...

BACKGROUND Renal disease in sarcoidosis may occur due to granulomatous interstitial nephritis. However, granulomatous interstitial nephritis in the absence of features of extrarenal sarcoid, or other causes, has been reported very rarely. In this report we describe seven such patients. METHODS Since 1995, we have identified a number of patients with biopsy-proven granulomatous interstitial ne...