larsen syndrome is a skeletal dysplasia (osteochondro-dysplasia) in which multiple dislocations of the large joints are the major feature . nosology in this group of disease, which constitutes 8% of mendelian disorders in man, is primarily based on clinical and radiological features. the underlying genetic defect is 3p21.1-p14.1 in the dominant type

Bismuth oxide kinetically stabilized by doping with a metastable structure of disordered fluorite ?-Bi2O3 has unique conductivity. Oxygen selective membranes at intermediate temperatures ~550?C, on the base cermet ?-Bi2O3/Ag, have highest potential for air separation and can be used to produce oxygen distributed multigeneration burning fossil carbon fuels. When searching optimal composition ?-B...

Almost all eukaryotic genes are conserved, suggesting that they have essential functions. However, only a minority of genes have detectable loss-of-function phenotypes in experimental assays, and multiple theories have been proposed to explain this discrepancy. Here, we use RNA-mediated interference in C. elegans to examine how knockdown of any gene affects the overall fitness of worm populatio...

Explanation ..................................................................................................... 227 Evaluation for acceptable daily intake ............................................................ 228 1. Biochemical aspects .......................................................................... 228 1.1 Absorption, distribution and excretion .................................

Stiff thin films on soft substrates are both ancient and commonplace in nature; for instance, animal skin comprises a stiff epidermis attached to a soft dermis. Although more recent and rare, artificial skins are increasingly used in a broad range of applications, including flexible electronics, tunable diffraction gratings, force spectroscopy in cells, modern metrology methods, and other devic...

Do regime change and market reform disrupt patterns of intergenerational mobility? China's political trajectory is distinctive from that of other communist regimes in two ways. During its first three decades, the regime enforced unusually restrictive barriers to elite status inheritance. And during the subsequent market transition, unlike most of its counterparts, the Communist Party survived i...

North American Journal of Fisheries ManagementVolume 43, Issue 3 p. 889-889 RetractionFree Access Retraction: Monitoring hatchery broodstock composition and genetic variation spring/summer Chinook Salmon in the Columbia River basin with multigeneration pedigrees This article retracts following: Hatchery Broodstock Composition Genetic Variation Spring/Summer Basin Multigeneration Pedigrees Rebek...