The formation of cadmium sulfide (CdS) particles in the gaps between the layers of the multilamellar vesicles is described, introducing a new pathway in the preparation of nanometer-scale particles. The in situ structural characterization of both the CdS particles and the vesicles as a reaction medium was performed in the early and final states of the process by using anomalous small-angle X-ra...

We adapted the highly successful scattering density profile (SDP) model, which is used to jointly analyze small angle x-ray and neutron scattering data from unilamellar vesicles, for use with data from fully hydrated, liquid crystalline multilamellar vesicles (MLVs). By using a genetic algorithm, this new method is capable of providing high PREPRINT: Journal of Applied Crystallography A Journal...

The small-angle X-ray and neutron scattering, time resolved X-ray small-angle and wide-angle diffraction coupled with differential scanning calorimetry have been applied to the investigation of unilamellar and multilamellar dimyristoylphosphatidylcholine (DMPC) vesicles in sucrose buffers with sucrose concentrations from 0 to 60%. Sucrose buffer decreased vesicle size and polydispersity and inc...

Most subunit vaccines require adjuvants in order to induce protective immune responses to the targeted pathogen. However, many of the potent immunogenic adjuvants display unacceptable local or systemic reactogenicity. Liposomes are spherical vesicles consisting of single (unilamellar) or multiple (multilamellar) phospholipid bi-layers. The lipid membranes are interleaved with an aqueous buffer,...

The production of vesicles, spherical shells formed from lipid bilayers, is an important aspect of their recent application to drug delivery technologies. One popular production method involves pushing a lipid suspension through cylindrical pores in polycarbonate membranes. However, the actual mechanism by which the polydisperse, multilamellar lipid suspension breaks up into a relatively monodi...

In this work, we attempted to design phospholipid bilayers tethered semiconducting metal oxide films. The layers assembled on compact monocomponent self-assembled monolayers (SAM) films were accomplished earlier; however, previous studies indicated a poor ability of these functionally reconstitute transmembrane proteins. Commercially available fluorine doped tin (FTO) sheet glass was chosen as ...

Small angle neutron scattering (SANS) is used to study the structures formed in water by a diblock copolymer EO6BO11 (having 6 ethylene oxide, EO, and 11 butylene oxide, BO, units). The data show that polymer solutions over a broad concentration range (0.05-20 wt %) contain vesicular structures at room temperature. Interestingly, these vesicles could be formed without any external energy input,...

New model of separated form factors is proposed for the evaluation of small-angle neutron scattering curves from large unilamellar vesicles. The validity of the model was checked by comparison to the model of hollow sphere. The model of separated form factors and hollow sphere model give reasonable agreement in the evaluation of vesicle parameters. PACS: 87.16.Dg, 61.12.Ex, 61.10.Eq Information...