Depression is the most common psychiatric disorder observed in Parkinson's disease (PD) patients, however the neural contribution to the high rate of depression in the PD group is still unclear. In this study, we used resting-state functional magnetic resonance imaging (fMRI) to investigate the underlying neural mechanisms of depression in PD patients. Twenty-one healthy individuals and thirty-...

BACKGROUND Major depressive disorder (MDD) has been associated with abnormal structure and function of the brain's affective network, including the amygdala and orbitofrontal cortex (OFC). However, it is unclear if alterations of resting-state function in this affective network are present at the initial onset of MDD. AIMS To examine resting-state function of the brain's affective network in ...

Antisocial Personality Disorder (APD) is a personality disorder that is most commonly associated with the legal and criminal justice systems. The study of the brain in APD has important implications in legal contexts and in helping ensure social stability. However, the neural contribution to the high prevalence of APD is still unclear. In this study, we used resting-state functional magnetic re...

The majority of previous neuroimaging studies have demonstrated both structural and task-related functional abnormalities in adolescents with online gaming addiction (OGA). However, few functional magnetic resonance imaging (fMRI) studies focused on the regional intensity of spontaneous fluctuations in blood oxygen level-dependent (BOLD) during the resting state and fewer studies investigated t...

The core neuropsychological processes underlying post-traumatic stress disorder (PTSD) have yet to be elucidated, and the association between anatomical and functional deficits in PTSD remains largely unknown. The aim of our study was to investigate the alterations in cortical thickness and amplitude of low-frequency fluctuation (ALFF) in PTSD patients resulting from motor vehicle accidents (MV...

Introduction Several methods have been applied to analyze the low-frequency fluctuations of resting state (RS) fMRI data. Among these approaches, the functional connectivity (FC) analysis uses a seed region to obtain FC cross-correlation (CC) maps with every other time series of the brain (1); the Regional Homogeneity (ReHo) approach (2) measures the coherence of one time series with those of i...

Background: To explore the brain function regions characteristics of the acupoint combination, this study observed activity changes in the brain regions of healthy volunteers after acupuncture at both Taixi (KI3) and Taichong (LR3) (KI3 + LR3) and KI3 alone using resting-state functional magnetic resonance imaging (fMRI). Methods and Materials: 30 healthy volunteers were randomly allocated into...

dear editor multiple sclerosis (ms) is the most common inflammatory demyelinating disease of the central nervous system. ms is characterized by dissemination in time and place. dissemination can be clinically (clinically definite multiple sclerosis) or radiologically by magnetic resonance imaging (mri). correct diagnosis of ms needs dissemination both in time and in place and also exclusion of ...

results of all the ms patients, 78 (95.1%) and 21 (25.6%) were positive for anti-vzv and vzv dna, respectively. statistical analysis of the pcr results showed a significant correlation between the abundance of vzv and ms disease (p < 0.001). however, there was no significant correlation between the abundance of anti-vzv antibodies and ms disease by the elisa method. conclusions these results su...

background: intravenous immunoglobulin (ivig) is an established treatment of immune mediated demyelinating neuropathy including guillain-barré syndrome and chronic inflammatory demyelinating polyneuropathy. recent trials suggest its efficacy in treating relapsing- remitting multiple sclerosis. ivig exerts a number of effects, which may be beneficial in treating multiple sclerosis (ms): reductio...