Recently, the algebraic theory of MV -algebras is intensively studied. In this paper, we extend the concept of derivation of $MV$-algebras and we give someillustrative examples. Moreover, as a generalization of derivations of $MV$ -algebraswe introduce the notion of $f$-derivations and $(f; g)$-derivations of $MV$-algebras.Also, we investigate some properties of them.

Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (alpha...

there are several kinds of hyperrings, for example, krasnerhyperrings, multiplicative hyperring, general hyperrings and$h_v$-rings. in a multiplicative hyperring, the multiplication isa hyperoperation, while the addition is a binary operation. in this paper, the notion of derivation on multiplicative hyperrings is introduced and some related properties are investigated. {bf keywords:} multiplic...

Vibrio harveyi luciferase and flavin reductase FRP are, together, a two-component monooxygenase couple. The reduced flavin mononucleotide (FMNH2) generated by FRP must be supplied, through either free diffusion or direct transfer, to luciferase as a substrate. In contrast, single-component bifunctional monooxygenases each contains a bound flavin cofactor and does not require any flavin addition...

The higher order oligomeric state of the Na,K-ATPase alphabeta heterodimer in cell membranes is the subject of controversy. We have utilized the baculovirus-infected insect cell system to express Na,K-ATPase with alpha-subunits bearing either His(6) or FLAG epitopes at the carboxyl terminus. Each of these constructs produced functional Na,K-ATPase alphabeta heterodimers that were delivered to t...

During T cell development in the thymus, pre-T cell receptor (TCR) complexes signal CD4(-) CD8(-) (double negative [DN]) thymocytes to differentiate into CD4(+) CD8(+) (double positive [DP]) thymocytes, and they generate such signals without apparent ligand engagements. Although ligand-independent signaling is unusual and might be unique to the pre-TCR, it is possible that other TCR complexes s...

The notion of $f$-derivations of UP-algebras is introduced, some useful examples are discussed, and related properties are investigated. Moreover, we show that the fixed set and the kernel of $f$-derivations are UP-subalgebras of UP-algebras,and also give examples to show that the two sets are not UP-ideals of UP-algebras in general.

IFN-alphabeta is a potent immunoregulatory cytokine involved in the defense against viral and bacterial infections. In this study, we describe an as yet undefined IFN-alphabeta-dependent pathway of IFN-gamma induction in mice. This pathway is based on a synergism of IFN-alphabeta and IL-18, and is independent of IL-12 signaling yet dependent on STAT4. In contradiction to current dogma, we show ...

The lack of CD95 in mice is associated with an accumulation of TCR alphabeta+ CD4- CD8- (double-negative (DN)) cells in the lymph nodes (LNs) and other organs. To test the hypothesis that these DN cells arise from TCR alphabeta+ CD8+ cells after activation via the TCR, we have crossed an MHC class I-restricted TCR transgene (tg) onto the lpr genotype to generate two TCR-transgenic experimental ...