We have used the technique of host cell reactivation of UV-irradiated herpes simplex virus type 1 as a measure of the repair capacity of three Bloom's syndrome skin fibroblast strains. At low multiplicity of infection (less than 6 x 10(-4) plaque-forming unit/cell), reactivation of the virus by the Bloom's syndrome strains was indistinguishable from that by normal strains. Reactivation at highe...

Infection of human neurons in vitro with varicella-zoster virus (VZV) at a low multiplicity of infection does not result in a cytopathic effect (CPE) within 14 days postinfection (dpi), despite production of infectious virus. We showed that by 28 dpi a CPE ultimately developed in infected neurons and that interferon gamma inhibited not only the CPE but also VZV DNA accumulation, transcription, ...

Tkeatment of tinea capitis (ringworm of the scalp) in children has always been unsatisfactory. The multiplicity of the drugs used and the procedures mentioned in the textbooks make it difficult to formulate a routine method of treatment. Local antiseptics by themselves are not of much value, as the drugs cannot penetrate the skin to the root of the hair and control the infection inside the hair...

Actinomycosis is a chronic and less common infectious process that established by Actinomyces israilii. Involvement of faciocervical region is more common than thorasic and visceral types and typically involves the angle of mandible and with less occurrence rate the upper jaw may also be involved. Periapical lesions of maxilla that involved in this process by Actinomyces israilii are rare and c...

Several independent lines of evidence indicate that interferon-mediated innate responses are involved in controlling herpes simplex virus type 1 (HSV-1) infection and that the viral immediate-early regulatory protein ICP0 augments HSV-1 replication in interferon-treated cells. However, this is a complex situation in which the experimental outcome is determined by the choice of multiplicity of i...

in this work are studied the jacobians of certain singular transformations and the corresponding measures which support the jacobian computations.