and Clinical Immunology, Ajou University School of Medicine, Suwon-si, South Korea; Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, South Korea; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea. Background: There have been a few reports of hypersensitivity reactions to Ranitidine ...

BACKGROUND The need for muscle relaxants in general anesthesia in different surgeries including cardiac surgeries, and the type of relaxant to be used considering its different hemodynamic effects on patients with heart disease can be of considerable importance. In this study, the hemodynamic effects of two muscle relaxants, Cisatracurium and Atracurium in patients whit low function of left ven...

Prune belly syndrome (PBS) is a rare congenital disease presenting characteristic triad of abdominal muscle deficiency, urinary tract abnormality, and cryptorchidism with associated anomalies various systems. We report the anesthetic management an infant PBS no obvious facial deformity in whom we encountered unanticipated difficult airway. Multiple attempts to secure airway different supraglott...

A new xanthine derivative bronchodilator, 1-methyl-3-propylxanthine (MPX), and 1-methyl-3-butylxanthine (MBX) were synthesized. We evaluated their relaxant effects on tracheal smooth muscle isolated from guinea pigs and pharmacokinetic characteristics in rats using 1,3-dimethylxanthine (theophylline, TPH) as the reference drug. Dose-dependent relaxant effects were observed in the concentration ...

To investigate the feasibility of a novel recording method for trans-intercostal evoked spinal cord potentials (Tic-ESCPs) and the properties of the waveforms, the potentials were recorded and analyzed in an animal model. In two beagle dogs, Tic-ESCPs were recorded at the left twelfth intercostal to fourth lumbar nerves following stimulation at the left eleventh intercostal nerve, either with o...

Bronchodilators are important agents in the treatment of asthma and chronic obstructive airways disease. Beta agonists, theophyllines, and antimuscarinic agents are the main drugs in current use, but others are under investigation. Although other actions may be important, these drugs produce bronchodilation either by a direct effect on airway smooth muscle or by inhibiting neural pathways. As o...