Water-soluble fluorescent conjugated polymer is a promising material which could be used as an optical platform in highly sensitive molecular sensors. In this paper, a simple label-free DNA sensor, which consisted of a poly(3-alkoxy-4-methylthiophene) and an aptamer, was used to detect L-argininamide (L-Arm). Due to the specific binding reaction between L-Arm and its aptamer, the proposed metho...

Abstract Difficulties in dating Mississippi Valley–type (MVT) mineral deposits and the often closely associated dolomitization have led to controversy regarding their origin. We report first radiometric ages for Gorno mining district northern Italy, an example of Alpine subclass MVT deposits. U-Pb hydrothermal carbonates pre- postdating ore-forming event show that base-metal mineralization occu...

Tracking algorithms for the GPS C/A code with an interference rejection capability based on state estimation technique are considered. A swept tone jamming signal is modeled as an autoregressive (AR) process and estimated jointly with the timing delay. A novel Mean-Value Theorem Particle Filter (MVT-PF) is applied to address the highly nonlinear measurement model and its performance is compared...

Huazhong University of Science & Technology, Hubei, China Nowadays the simultaneous PET/MRI is being paid more and more attentions. Since MRI provides a high resolution, unsurpassed soft tissue contrast imaging and PET reveal the metabolism progress in molecular level, it is reasonable to believe the PET/ MRI will be a powerful tool to improve the understanding of pathogenesis and mechanism of ...

Schultheiss et al. [3]. The article by Lang et al. [4] points out the interdisciplinary approach that is required to select an optimal individual therapy for a given patient based on clinical presentation, underlying diseases, extension of thrombosis, and the patient’s comorbidities. A particular focus is therefore put on the surgical therapeutic options. A specific clinical challenge is a PVT ...

We propose estimating the scale parameter (mean of eigenvalues) scatter matrix an unspecified elliptically symmetric distribution using weights obtained by solving Tyler's M-estimator matrix. The proposed weights-based estimate (TWE) is then used to construct affine equivariant as a weighted sample covariance normalized weights. develop unified framework for unknown tail elliptical (such degree...

Abstract Introduction Ventricular arrhythmias (VA) represent a common complication of myocardial infarction (MI). Typically, they occur in two scenarios: during acute MI, related to ongoing ischemia, as ventricular tachycardia (VT) or fibrillation (VF), the context late phase presence scar, monomorphic VT (mVT). Despite above, their occurrence may be atypical. Clinical Case 55–year–old man affe...

Soon after its discovery, the attempts to develop anti-AIDS therapeutics focused on the retroviral protease (PR)-an enzyme used by lentiviruses to process the precursor polypeptide into mature viral proteins. An urgent need for the three-dimensional structure of PR to guide rational drug design prompted efforts to produce milligram quantities of this enzyme. However, only minute amounts of PR w...

This study investigated effects of caffeine ingestion (8 mg/kg) on maximum voluntary torque (MVT) and voluntary activation of the quadriceps during isometric, concentric and eccentric contractions. Fourteen subjects ingested caffeine and placebo in a randomized, controlled, counterbalanced, double-blind crossover design. Neuromuscular tests were performed before and 1 h after oral caffeine and ...

Abstract The minimum variation timescale (MVT) of soft gamma-ray repeaters can be an important probe to estimate the emission region in pulsar-like models, as well Lorentz factor and radius possible relativistic jet burst (GRB)–like thus revealing their progenitors physical mechanisms. In this work, we systematically study MVTs hundreds X-ray bursts (XRBs) from SGR J1935+2154 observed by Insigh...