PURPOSE We evaluated the efficacy and tolerability of mycophenolate mofetil in patients with treatment refractory interstitial cystitis/painful bladder syndrome. MATERIALS AND METHODS A total of 210 patients with interstitial cystitis/painful bladder syndrome were to be randomized into a multicenter, placebo controlled trial using a 2:1 randomization. Participants in whom at least 3 interstit...

background: the purpose of this study was to characterize the pharmacokinetic parameters of mycophenolic acid (mpa) in iranian kidney transplant patients. methods: plasma mpa concentration of mycophenolate mofetile (mmf) 1 gram two times a day was measured in 21 iranian kidney transplant recipients receiving treatment. patients who entered the study had been transplanted for more than 3 months ...

BACKGROUND Despite the advances in the treatment of chronic hepatitis B virus (HBV) infection, liver transplantation (LT) remains the only hope for many patients with end-stage liver diseases resulting from HBV. OBJECTIVES The aim of this study was to investigate the rate of HBV recurrence in cases that had undergone LT due to the HBV related liver cirrhosis. PATIENTS AND METHODS Forty-nine...

The adverse effects of mycophenolate mofetil on the colon are well known. However, isolated small intestinal involvement resulting in diarrhea and severe weight loss is infrequently reported in the literature. We present the case of a 45-year-old woman on mycophenolate mofetil following renal transplant, who presented with abdominal pain and weight loss. An esophagogastroduodenoscopy and colono...

MATERIAL and METHODS: A total of 60 male Albino rats (Wistar strain) were equally divided into four groups as follows: Mycophenolate mofetil group (MMFG), rapamycin group (RAPG) and no-treatment group (NTG) receiving 15 mL 3.86% glucose solution, and control group (CG) receiving daily intraperitoneal injection of 15 mL normal saline. Mycophenolate mofetil and rapamycin were administered orally ...