Myelin-Oligodendrocyte Glycoprotein (MOG) is an adhesive molecule responsible for myelin sheath structural integrity and maintenance. Patients with spectrum of inflammatory demyelinating disease particularly in central nervous system are reported to have antibodies against this protein. Diseases such as multiple sclerosis, clinically isolated syndrome, neuro-myelitis optica (NMO) spectrum disor...

Background: Idiopathic longitudinally extensive transverse myelitis is defined as a focal spinal cord lesion that involves three or more segments of the shown by neuroimaging, and results in profound disability. The clinical picture patient with idiopathic advanced often dramatic may consist paraparesis tetraparesis, sensory disturbances, pelvic dysfunction. common manifestation neuromyelitis o...

Myelitis is a rare complication of Schistosoma mansoni, and is characterized by a dramatic involvement of the lower part of the spinal cord [1 , 2]. Early antischistosomal therapy is able to improve markedly clinical signs [3, 4J. Myelography and CT (3, 5-1 OJ are normal in most cases of Schistosoma mansoni transverse myelitis (2, 1 OJ . As far as we know, no MR studies have been reported. We p...

Transverse myelitis (TM) includes a pathobiologically heterogeneous syndrome characterized by acute or subacute spinal cord dysfunction resulting in paresis, a sensory level, and autonomic (bladder, bowel, and sexual) impairment below the level of the lesion. Etiologies for TM can be broadly classified as parainfectious, paraneoplastic, drug/toxin-induced, systemic autoimmune disorders, and acq...

Abstract Introduction : The new pandemic has highlighted ways of clinical presentation severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) including a possible link to central nervous system (CNS) manifestation. Case report We present case transverse myelitis following SARS-CoV infection in 34-year-old man who presented with bilateral lower-extremity weakness and urinary retention. Cer...

The hepatitis B virus (HBV) is an important international cause of infectious acute and chronic liver diseases. HBV vaccines were developed to combat the potential life-threatening effects of HBV infection. Published case histories, retrospective reviews and analyses of epidemiological data report on the onset of immune-mediated myelitis after recombinant HBV vaccination, mostly in adults with ...

In the last few years, substantial evidence has been provided on peripheral nervous involvement in infection by hepatitis C virus (HCV), whilst central nervous involvement is rare. Here, we report a case of acute transverse myelitis in a woman developing 4 years after documented HCV seropositivity, associated with intrathecal anti-HCV protein IgG. Isoelectrofocusing of all CSF samples before an...

To cite: Jabbari E, Marshall CR, Longhurst H, et al. Pract Neurol 2015;15:49–52. INTRODUCTION Transverse myelitis requires careful investigation, as although many causes respond acutely to immunomodulation, the longer term management depends upon its precise cause. We describe a patient presenting acutely with a corticosteroidresponsive longitudinally extensive transverse myelitis and granuloma...