نتایج جستجو برای: myokine
تعداد نتایج: 312 فیلتر نتایج به سال:
Abstract The novel myokine myonectin is predominantly expressed in skeletal muscle and involved the regulation of metabolic homeostasis. A putative association between type 2 diabetes mellitus (T2DM) has been discussed controversially current literature. purpose this study was to investigate T2DM at different ages. We measured 410 vascular risk patients with a mean age 66 years. Myonectin did n...
This paper summarizes the various effects of neurotrophins in skeletal muscle and how these proteins act as potential regulators of the maintenance, function, and regeneration of skeletal muscle fibers. Increasing evidence suggests that this family of neurotrophic factors influence not only the survival and function of innervating motoneurons but also the development and differentiation of myob...
FNDC4 is a secreted factor sharing high homology with the exercise-associated myokine irisin (FNDC5). Here we report that Fndc4 is robustly upregulated in several mouse models of inflammation as well as in human inflammatory conditions. Specifically, FNDC4 levels are increased locally at inflamed sites of the intestine of inflammatory bowel disease patients. Interestingly, administration of rec...
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