BACKGROUND Several organizations and individual authors have been proposing quality indicators for the assessment of clinical care in HIV/AIDS patients. Nevertheless, the definition of a consensual core set of indicators remains controversial and its practical use is largely limited. This study aims not only to identify and characterize these indicators through a systematic literature review bu...

This paper discusses a three year initiative to transform classical systems engineering (SE) measures into leading indicators, including the resulting guidance information that has been developed and future research directions. Systems engineering leading indicators are measures for evaluating the effectiveness of the systems engineering activities on a program in a manner that provides informa...

The effectiveness of methadone maintenance treatment is beyond any doubt, but there remains some incertitude about the appropriate and effective dosage and the objectives that should be achieved by this therapy. Some authors maintain that only doses higher than 50-60 mg/day ought to be considered effective, since only these block all the opioid receptors. But others propose the use of doses adj...

Sympathetic denervation is associated with many diseases. Most cutaneous external monitoring indicators are non-invasive and used widely in clinical medicine. The external monitoring indicators of sympathetic denervation are reviewed to facilitate the clinical diagnosis of sympathetic diseases and the results of sympathectomy. Useful indicators of sympathetic denervation include sweating, warm ...