Alzheimer's disease (AD) is one of the main causes dementia worldwide, whereby neuronal death or malfunction leads to cognitive impairment in elderly population. AD highly prevalent, with increased projections over next few decades. Yet current diagnostic methods for occur only after presentation clinical symptoms. Evidence literature points potential mechanisms induction beginning before sympt...

ABSRACT Nanoparticle arrays biologically derived from an electrochemicallycontrolled site-specific biomineralization were fabricated on a gold substrate through the immobilization process of biomolecules. The work reported herein includes the immobilization of ferritin with various surface modifications, the electrochemical biomineralization of ferritins with different inorganic cores, the fabr...

This review article discusses and documents the basic concepts and principles of nano/biosensors. More specifically, we comment on the use of Chemical Force Microscopy (CFM) to study various aspects of architectural and chemical design details of specific molecules and polymers and its influence on the control of chemical interactions between the Atomic Force Microscopy (AFM) tip and the sample...

The anxiety and pain associated with frequent finger pricking has always been troublesome for diabetics measuring blood glucose (BG) in their daily lives. For this reason, a reliable glucose monitoring system that allows noninvasive measurements is highly desirable. Our main objective is to develop a biosensor that can detect low-level glucose in saliva (physiological range 0.5-20 mg/dL). Saliv...

Background The particularities of gold nanoparticles (AuNP’s) have stimulated different areas of research in recent years. The exploitation of the optical properties, electronic and magnetic materials has allowed these his job in different fields of application, such as the construction of biosensors in gradual release system for drugs, lubricants, solar cells, catalysis and other [1]. The prop...

The discovery of graphene and its unique properties has inspired researchers to try to invent other two-dimensional (2D) materials. After considerable research effort, a distinct "beyond graphene" domain has been established, comprising the library of non-graphene 2D materials. It is significant that some 2D non-graphene materials possess solid advantages over their predecessor, such as having ...

Surface layer as the outer protective coverage of bacteria and archaea are two-dimensional crystalline and symmetrical arrays of proteins that recently attract a lot of attention for biologist scientists. The surface layers of bacteria are usually 5 to 10 nm in diameter and represent highly porous protein lattices with uniform size and morphology with the pore sizes of 2 to 8 nm. The crucial an...

In Nanosciences, connecting an individual nano-object remains a technological bottleneck. The way nano-objects can be coupled to the micro and macroscopic environment without loosing their intrinsic properties is the main issue of so-called “NanoAddressing”. In LAAS-CNRS, the “Nanoaddressing/Nanobiotechnologies” group, created two years ago, develops and validate new concepts for achieving smar...

Smart (Nano) materials with biosensing functions posses enormous potential in development of new generation of stable biosensors, chemical sensors, and actuators. Recently, there is a considerable interest in using TiO(2) nanostructured materials as a film-forming material since they have high surface area, optical transparency, high bio-compatibility, and relatively good conductivity. In this ...