The recent melamine crisis in China has pointed out a serious deficiency in current food control systems, namely, they specifically focus on selected known compounds. This targeted approach allowed the presence of melamine in milk products to be overlooked for a considerable time. To avoid such crises in the future, we propose that nontargeted screening methods need to be developed and applied....

Changes of neural oscillations at a variety of physiological rhythms are effectively associated with cognitive performance. The present study investigated whether the directional indices of neural information flow (NIF) could be used to symbolize the synaptic plasticity impairment in hippocampal CA3-CA1 network in a rat model of melamine. Male Wistar rats were employed while melamine was admini...

OBJECTIVE To investigate the renal outcomes of children after exposure to low dose melamine in Hong Kong. DESIGN Cross sectional study. SETTING Special assessment centres, Hong Kong. PARTICIPANTS 3170 children (1422 girls and 1748 boys) aged 12 years or less referred from territory-wide primary care clinics after daily consumption for one month or more of milk products tainted with melami...

Melamine is an organic nitrogenous compound widely used as an industrial chemical, and it has been recently reported by us that melamine has a toxic effect on the female reproductive system in mice, and renders females subfertile; the molecular basis, however, has not been adequately assessed. In the present study, we explore the underlying mechanism regarding how melamine compromises fertility...

Multivariate calibration (MVC) and near-infrared (NIR) spectroscopy have demonstrated potential for rapid analysis of melamine in various dairy products. However, the practical application of ordinary MVC can be largely restricted because the prediction of a new sample from an uncalibrated batch would be subject to a significant bias due to matrix effect. In this study, the feasibility of using...

The objective of this project was to use sucrose as a partial substitute for melamine in the synthesis of sucrose–melamine-formaldehyde (SMF) resin. The SMF was synthesized in a base condition. The wet bonding strength, shelf life, and formaldehyde emission of the SMF resin were determined. Fourier transform infrared spectroscopy (FT-IR) and mass spectroscopy (MS) were employed to analyze the c...

A simple, precise, accurate, and validated reverse-phase HPLC method was developed for the determination of melamine in milk (pasteurized and UHT milk) and dairy products (powdered infant formula, fruit yogurt, soft cheese, and milk powder). Following extraction with acetonitrile:water (50:50, vol/vol), samples were purified by filter (0.45 μm), separated on a Nucleosil C8 column (4.6 mm × 250 ...

The electrochemiluminescence (ECL) of Ru(bpy)(3)(2+) at bare and single-wall carbon nanotube (SWNT) modified glassy carbon (GC) electrodes has been employed for the determination of melamine for the first time, giving a linear response (R(2) = 0.99682) for melamine concentration from 1.0 × 10(-10) to 1.0 × 10(-5) M at a bare GC electrode in pH 10 borate buffer, and the detection limit is 1.0 × ...

Biomass-based highly porous carbons with excellent performances in aqueous electrolyte-based supercapacitors have been developed. The synthesis of these materials is based on the chemical activation of biomass-based hydrochar. The addition of melamine to the activation mixture leads to porous carbons with a porosity consisting of micropores/small mesopores. Furthermore, melamine promotes the in...

A high-performance liquid chromatography method is described in this paper. The method uses NH(2) column and 97% acetonitrile eluate to determine the insecticide cyromazine and metabolite melamine residues in milk and pork. Samples were treated with NaOH and extracted with acetonitrile containing 20% NH(4)OH. Target analytes of samples were cleaned up and concentrated by C(18) column solid-phas...