نتایج جستجو برای: nanostructured lipid carriers

تعداد نتایج: 220080  

Journal: :Biomaterials Science 2021

Dasa-NLC could significantly inhibit the corneal neovascularization.

Journal: :Scientia Pharmaceutica 2021

The aim of this study was to understand the effect high shear homogenization (HSH) and ultrasonication (US) on physicochemical properties blank olanzapine loaded nanostructured lipid carriers (NLCs) along with their drug loading potential release profiles from formulated particles. NLCs were prepared different ratios Compritol Miglyol as solid liquid lipids, respectively, under changing HSH US ...

Journal: :Journal of Drug Delivery and Therapeutics 2023

Objective: The current work involves formulation development of nanostructured lipid carrier (NLC) eperisone hydrochloride (EPE) using quality by design (QbD) approach.
 Materials and Methods: Initial screening solid liquid lipids was performed based on the Hansen solubility parameters EPE later confirmed saturation studies. optimum identified three-squared randomized full factorial design...

Journal: :Molecules 2014
Yang Chu Dan Li Yi-Fan Luo Xiao-Jin He Ming-Yan Jiang

Curcumin, a phenolic antioxidant compound derived from the rhizome of the turmeric plant Curcuma longa, has proven to be a modulator of intracellular signaling pathways that control cancer cell growth, inflammation, invasion and apoptosis, revealing its anticancer potential. In this study, a Glycyrrhetinic Acid-Modified Curcumin-Loaded Nanostructured Lipid Carrier (Cur-GA-PEG-NLC) was prepared ...

Journal: :the iranian journal of pharmaceutical research 0
alwan al-qushawi dept. pharmacology, faculty of vet med, university of tehran ali rassouli dept. pharmacology, faculty of vet med, university of tehran fatemeh atyabi dept. pharmaceutics, faculty of pharmacy, tehran university of medical sciences, seyed mostafa peighambari dept. avian pathology, faculty of veterinary medicine, university of tehran mehdi esfandyari-manesh nanotechnology research center, tehran university of medical sciences gholamreza shams dept. pharmacology, faculty of veterinary medicine, university of tehran

tilmicosin (tlm) is an important antibiotic in veterinary medicine with low bioavailability and safety. this study aimed to formulate and evaluate physicochemical properties, storage stability after lyophilization and antibacterial activity of three tlm-loaded lipid nanoparticles (tlm-lnps) including solid lipid nanoparticles (slns), nanostructured lipid carriers (nlcs) and lipid-core nanocapsu...

2015
Ramaiyan Velmurugan Subramanian Selvamuthukumar

The research focuses on the development and optimization of ifosfamide nanostructured lipid carriers for oral delivery with the application of response surface methodology. The objectives of the study were to develop a formulation for ifosfamide to be delivered orally, overcome the instability of the drug in acidic environment during oral administration, to sustain the release, drug leakage dur...

2015
Jessica Otarola Adriana Guillermina Lista Beatriz Fernández Band Mariano Garrido

A simple and fast capillary electrophoresis method has been developed to determine the amount of piroxicam loaded in a drug delivery system based on nanostructured lipid carriers (NLCs). The entrapment efficiency of the nanostructured lipid carrier was estimated by measuring the concentration of drug not entrapped in a suspension of NLC. The influence of different parameters on migration times,...

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