نتایج جستجو برای: nasopharyngeal diseases

تعداد نتایج: 863034  

Journal: :PLoS ONE 2009
Shota Nakamura Cheng-Song Yang Naomi Sakon Mayo Ueda Takahiro Tougan Akifumi Yamashita Naohisa Goto Kazuo Takahashi Teruo Yasunaga Kazuyoshi Ikuta Tetsuya Mizutani Yoshiko Okamoto Michihira Tagami Ryoji Morita Norihiro Maeda Jun Kawai Yoshihide Hayashizaki Yoshiyuki Nagai Toshihiro Horii Tetsuya Iida Takaaki Nakaya

With the severe acute respiratory syndrome epidemic of 2003 and renewed attention on avian influenza viral pandemics, new surveillance systems are needed for the earlier detection of emerging infectious diseases. We applied a "next-generation" parallel sequencing platform for viral detection in nasopharyngeal and fecal samples collected during seasonal influenza virus (Flu) infections and norov...

2015
Elif Aktas Burcu Sahin Nazan Ciledag Kemal Niyazi Arda Emrah Caglar Inci Ergurhan Ilhan

BACKGROUND Nasopharyngeal carcinoma is a rarely seen tumor in childhood. It is mostly detected late as the clinical features are similar to other childhood tumors which affect the nasopharynx and adenoidal hypertrophy. Therefore, the radiological features of childhood tumors of the nasopharynx must be well known. The aim of this study was to investigate the contribution of MR imaging features o...

Journal: :iranian journal of cancer prevention 0
puneet kumar bagri dept of radiation oncology, acharya tulsi regional cancer treatment & research institute, bikaner-334003, rajasthan, india mukesh kumar singhal dept. of radiation oncology, acharya tulsi regional cancer treatment & research institute, bikaner-334003, rajasthan, india daleep singh dept of radiation oncology, acharya tulsi regional cancer treatment & research institute, bikaner-334003, rajasthan, india akhil kapoor dept. of radiation oncology, acharya tulsi regional cancer treatment & research institute, bikaner-334003, rajasthan, india shankar lal jakhar dept. of radiation oncology, acharya tulsi regional cancer treatment & research institute, bikaner-334003, rajasthan, india neeti sharma dept. of radiation oncology, acharya tulsi regional cancer treatment & research institute, bikaner-334003, rajasthan, india

background: this prospective study was conducted to evaluate and compare the efficacies of nasopharyngoscopy and ct scan in the diagnosis of local failure of external beam radiotherapy (ebrt) for nasopharyngeal carcinoma. methods: total 52 patients of histopathologically proven nasopharyngeal carcinoma treated with external beam radiotherapy (ebrt), were included in this study. for every patien...

2017
Yuan Tian Yan Song Weiliang Bai Xiulan Ma Zhong Ren

Nasopharyngeal cancer is a type of malignant tumor with a high rate of incidence. Cancer stem cells are regarded as one of the main causes for the formation and recurrence of nasopharyngeal cancer. CXC chemokine receptor type 4 (CXCR4) has been reported to perform an important role in cancer; however, the association between CXCR4 and nasopharyngeal cancer stem cells remains unclear. The presen...

Journal: :Genetics and molecular research : GMR 2015
X J Zhou B R Lin Y Wang

The gene glutamate receptor, ionotropic, N-methyl D-aspartate 2A (GRIN2A) is associated with development and neuron viability, and our previous studies showed it to be substantially methylated in nasopharyngeal carcinoma, indicating a link to this disease. The aim of this work was to investigate GRIN2A expression and its clinical significance in nasopharyngeal carcinoma, in contrast to nasophar...

Journal: :Molecular cancer therapeutics 2013
Jeremy P H Chow Wing Yu Man Mao Mao Han Chen Florence Cheung John Nicholls Sai Wah Tsao Maria Li Lung Randy Y C Poon

Nasopharyngeal carcinoma is a rare but highly invasive cancer. As options of agents for effective combination chemoradiotherapy for advanced nasopharyngeal carcinoma are limited, novel therapeutic approaches are desperately needed. The ubiquitin ligase CHFR is known to target PARP1 for degradation and is epigenetically inactivated in nasopharyngeal carcinoma. We present evidence that PARP1 prot...

2016
Ping Li Yongru Liu Zhu Yu Xing Xiao Gang Chen Zuyun Li

Background: Aberrant expression of STAT4 has been validated in different cancers. However, its role in nasopharyngeal carcinoma (NPC) remains unidentified. The purpose of the current study was to investigate the clinical significance of STAT4 and its potential role in the carcinogenesis and deterioration of NPC. Materials and Methods: Expression of STAT4, as well as EGFR and P53 in 393 NPC pati...

2006
Li-Bing Song Mu-Sheng Zeng Wen-Ting Liao Ling Zhang Hao-Yuan Mo Wan-Li Liu Jian-Yong Shao Qiu-Liang Wu Man-Zhi Li Yun-Fei Xia Wen-Lin Huang Goberdhan P. Dimri Vimla Band Yi-Xin Zeng

The Bmi-1 oncoprotein regulates proliferation and oncogenesis in human cells. Its overexpression leads to senescence bypass in human fibroblasts and immortalization of human mammary epithelial cells. In this study, we report that compared with normal nasopharyngeal epithelial cells (NPEC), Bmi-1 is overexpressed in nasopharyngeal carcinoma cell lines. Importantly, Bmi-1 was also found to be ove...

2013
Jeremy P.H. Chow Wing Yu Man Mao Mao Han Chen Florence Cheung John Nicholls Sai Wah Tsao Maria Li Lung Randy Y.C. Poon

Nasopharyngeal carcinoma is a rare but highly invasive cancer. As options of agents for effective combination chemoradiotherapy for advanced nasopharyngeal carcinoma are limited, novel therapeutic approaches are desperately needed. The ubiquitin ligase CHFR is known to target PARP1 for degradation and is epigenetically inactivated in nasopharyngeal carcinoma. We present evidence that PARP1 prot...

2016
Pietro Genova Francesco Brunetti Emilie Bequignon Filippo Landi Vincenzo Lizzi Francesco Esposito Cecile Charpy Julien Calderaro Daniel Azoulay Nicola de’Angelis

BACKGROUND Solitary splenic metastases are a rare occurrence, and the nasopharyngeal carcinoma represents one of the most uncommon primary sources. The present study aimed to describe a rare case of a solitary single splenic metastasis from nasopharyngeal carcinoma and to assess the number of cases of isolated nasopharyngeal carcinoma metastases to the spleen reported in the literature. MAIN ...

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