Yaumatei Dermatology Clinic, 12/F, Yaumatei Specialist Clinic (New Extension), 143 Battery Street, Yaumatei, Kowloon, Hong Kong An eleven-month-old boy presented with increasing number of yellowish papules on scalp, trunk and limbs soon after birth. Skin biopsy revealed juvenile xanthogranuloma. He was also found to have multiple café-au-lait macules. The clinical course, complications and asso...

A 38-year-old woman presented to the emergency room with a 7day history of severe headache, nausea, and vomiting . The neurologic examination was normal. Both CT and MR showed a mass at the foramen of Monro (Fig . 1). The CT appearance was atypical for colloid cyst; therefore, the diagnosis of xanthogranuloma was suggested. The mass was surgically removed , and the final pathologic diagnosis wa...

Systemic form of juvenile xanthogranuloma with involvement of liver and bone marrow is reported in a 2-month-old female infant who presented with hepatosplenomegaly, severe anemia, and thrombocytopenia. There was no skin lesion, nor bone lesion. The enlarged liver has generalized yellowish spots. The diagnosis of juvenile xanthogranuloma was made by pathologic findings of marrow and portal trac...

Juvenile xanthogranuloma is a non-Langerhans cell histiocytosis that typically affects children, but several cases have been reported in adults, some in connection with hematologic malignancies. We present the case of a 61-year-old woman with multiple xanthogranulomas who developed a follicular lymphoma after 4 years of follow-up. After 6 months of treatment with chemotherapy and rituximab, the...

BACKGROUND Head and neck cancer is often managed with a combination of surgery, radiation therapy, and chemotherapy, and skin toxicity is not uncommon. Xanthogranuloma is a pathological finding resulting from an inflammatory reaction that has not been previously reported following head and neck radiation therapy. CASE PRESENTATION A patient with squamous cell carcinoma of the oropharynx, trea...

Juvenile xanthogranuloma is the most common form of non-Langerhans cell histiocytosis. It manifests clinically as a red-yellow papule, usually showing spontaneous remission. The diagnosis is based on clinical and histological findings. We report the use of dermoscopy (“setting sun” pattern) as an adjuvant tool in the diagnosis of juvenile xanthogranuloma in a female patient presenting with a 2-...

Xanthogranuloma is an uncommon tumor in the ocular adnexa. It usually presents as diffuse lid swelling with or without orbital involvement. Xanthogranulomas can be associated with systemic comorbidities. They are diagnosed by their characteristic pathological finding. They are further subclassified based on immunohistochemistry. We present two cases with lid swelling which were diagnosed to be ...

INTRODUCTION Orbital masses in adults are often caused by systemic diseases or are associated with systemic manifestations. Juvenile xanthogranuloma as a cause is rare and unreported in Africa. We present clinical features, management, and outcomes of bilateral orbital adult onset juvenile xanthogranuloma. CASE PRESENTATION A 27 year old Nigerian woman presented with bilateral upper-lid lumps...

INTRODUCTION Differentiation of cystic mass lesions of the sellar and parasellar regions may pose a diagnostic dilemma for physicians, neurosurgeons, radiologists and pathologists involved in treating patients with these entities. A considerable number of tumors previously identified as craniopharyngiomas may, in fact, have been xanthogranulomas. We report a case of pituitary dysfunction caused...