INTRODUCTION Scleritis is a rare, progressive and serious disease, the signs of which are inflammation and edema of episcleral and scleral tissues and is greatly associated with systemic rheumatoid diseases. PURPOSE To perform a prospective and comparative study between ophthalmologic manifestations, serologic findings and therapeutic response of patients with isolated scleritis and scleritis...

PURPOSE To analyse clinical features, systemic associations, treatment and visual outcomes in Japanese patients with scleritis. METHODS Clinical records of 83 patients with scleritis who presented between 1998 and 2008 to the Ocular Inflammation Service of the Kyorin Eye Center, Tokyo, were reviewed. RESULTS Of the 83 patients, 57 (69%) had diffuse anterior scleritis, 9 (11%) had nodular an...

PURPOSE To report the histopathological findings in a case of severe Acanthamoeba sclerokeratitis (ASK). PATIENT AND METHODS A 46-year-old patient was referred to the Department of Ophthalmology of Mie University Hospital because of a severe corneal ulcer of the right eye of 6 months' duration. Our initial examination showed a ring-shaped corneal opacity with extensive epithelial defects and ...

BACKGROUND Although pterygium excision with conjunctival autograft is a widely performed surgical procedure, surgically induced necrotizing scleritis (SINS) following such surgery is extremely rare. METHODS A 68-year-old man underwent nasal pterygium excision with conjunctival autograft uneventfully. On postoperative day 17, the conjunctival graft was avascular, with epithelial defect. Althou...

scleritis is achieved through observation of sun set glow fundus and neurologic or dermatologic signs not seen in posterior scleritis. Posterior scleritis is also usually unilateral, and T-sign is a unique characteristic of this disease. Recently, there have been some reports, especially in Japan, of posterior scleritis appearing concurrently with VKH disease in patients; Kouda et al. [4] repor...

We report a patient with necrotising scleritis in whom infliximab was used for short-term steroid-sparing while rituximab took effect. This enabled disease control without requiring an extended period of high-dose corticosteroid administration or the concurrent use of cyclophosphamide.

we report a 32-year-old man with behçet’s disease who had simultaneous bilateral anterior uveitis, unilateral nodular scleritis and occlusive vasculitis with retinal hemorrhages at the same time. though scleritis is not considered within  the classical features of behçet’s disease behçet’s disease should be contemplated in the scleritis etiology.