BACKGROUND/AIM The aim of this study was to describe the results of amniotic membrane transplantation (AMT) in patients with bacterial and herpetic stromal keratitis. MATERIALS AND METHODS This was a retrospective chart review study including 42 patients with herpetic keratitis (group 1) and 42 patients with bacterial keratitis (group 2). AMT was performed in addition to antimicrobial therapy...

Contact lens-related complications are common, affecting around one third of wearers, although most mild and easily managed. lenses have well-defined anatomical physiological effects on the ocular surface can result in other consequences due to presence a biologically active material. A contact lens interacts with tear film, surface, skin, endogenous environmental microorganisms, components car...

Peripheral ulcerative keratitis (PUK) is an inflammatory condition leading to ocular morbidity. It can be associated with underlying autoimmune diseases which often goes undetected if the manifestation precedes systemic manifestation. The objective of this case report highlight that, management such entity challenging. We present a 36-year- old female diminution vision, PUK necrotizing scleriti...

Corneal infections are frequent and potentially vision-threatening diseases, and despite the significance of the immunological response in animal models of microbial keratitis (MK), it remains unclear in humans. The aim of this study was to describe the cytokine profile of tears in patients with MK. Characteristics of ocular lesions such as size of the epithelial defect, stromal infiltration, a...

OBJECTIVE The study aims to assess the both individual behavior and correlations of stromal fibrillary component (SFC) and vascular density (VD) in relation with Srigley architectural patterns of prostate carcinoma. MATERIALS AND METHODS Digital images of prostate adenocarcinoma labeled following both Gleason and Srigley systems were acquired with ×20 objective from two serial sections, 340 f...

BACKGROUND Corneal ulcers are one of the most common eye problems in the horse and can cause varying degrees of visual impairment. Secondary infection and protease activity causing melting of the corneal stroma are always concerns in patients with corneal ulcers. Corneal collagen cross-linking (CXL), induced by illumination of the corneal stroma with ultraviolet light (UVA) after instillation o...

acanthamoeba keratitis is a vision- threatening infection and the most important risk factors are contact lenses characteristic symptoms include disproportionately severe ocular pain, epithelial ulcer, ring stromal infiltrate and resistance to antimicrobial treatment. the aim is to report the first cases of acanthamoeba keratitis in yazd in a retrospective study confirmed on histopathological a...

PURPOSE To report an unusual case of herpetic bullous keratitis misdiagnosed as a case of pseudophakic bullous keratopathy with secondary glaucoma. RESULTS A retrospective analysis of the case record of a 60-year-old man who had earlier undergone bilateral cataract surgery, was done. He presented with a complaint of decrease in vision in the right eye of 20 days duration. On examination, corn...

OBJECTIVE To report a patient with severe Chrysosporium keratitis successfully treated by voriconazole. METHOD Case report. RESULTS A 37-year-old healthy male presented with irritation, pain and reduced vision in his left eye after mud contamination. Examination demonstrated corneal stromal infiltration, endothelial plaque and hypopyon. Corneal scrapings demonstrated numerous septate hyphae...

Amniotic membrane transplantation (AMT) promotes rapid epithelialization and reduces stromal inflammation and ulceration in HSV-1 keratitis. 18 patients with non-healing epithelial defect or corneal ulcer caused by herpetic keratitis were included in the study. All patients were treated by AMT. Corneal epithelial cells in patients suffering from herpetic keratitis secreted 5+/-4.8 pg/ml of IL-1...