نتایج جستجو برای: neisseria meningitids
تعداد نتایج: 10458 فیلتر نتایج به سال:
Non-gonococcal non-meningococcal Neisseria sp. normally inhabits the upper respiratory tract in human beings. There are four recognized species within the genus: N. sicca, N. mucosa, N. subflava and N. flavescens. They have low pathogenicity. Among them, Neisseria mucosa and N. sicca have been described to cause endocarditis. To our knowledge, this is the fourth reported case of prosthetic valv...
Background: Although the conventional vaccines have been instrumented in the incidence of many infectious diseases, the advances in genetic engineering and bioinformatics have provided the opportunity for developing improved and new vaccines.Methods: Reverse vaccinology was pioneered by a group of researchers investigating development of a vaccine against serogroup B Neisseria meningitidis. Rev...
Background: Despite the availability of a wide range of antibiotics, bacterial infections are among important challenges for the healthcare system. Therefore, the introduction of new antimicrobial preparations such as platelet-rich plasma (PRP) could be suggested theoretically as a preventive measure for bacterial infections. We aimed to evaluate the in vitro antibacterial activity of PRP again...
The tetraspanins are a superfamily of transmembrane proteins with diverse functions and can form extended microdomains within the plasma membrane in conjunction with partner proteins, which probably includes receptors for bacterial adhesins. Neisseria meningitidis, the causative agent of meningococcal disease, attaches to host nasopharyngeal epithelial cells via type IV pili and opacity (Opa) p...
We have identified genes required for competence of Neisseria meningitidis, a naturally transformable human pathogen. Although not comprehensive, our analysis identified competence-defective mutants with transposon insertions in genes not previously implicated in this process in Neisseria.
objective: the lack of adequate recognition of health importance of non-hiv reproductive health infections (rhis) in nigeria has led into this study, which was to determine clinical pathogens in non-hiv rhi in nigeria using a tertiary health facility as case study. materials and methods: a nine-year investigation was carried out between 1997 and 2005 on 4047 (n = 1626 males; n = 2421 females) p...
The three species Neisseria meningitidis, Neisseria gonorrheae, and Neisseria lactamica are often regarded as highly recombining bacteria. N. meningitidis has been considered a paradigmatic case of the "semiclonal model" or of "epidemic clonality," demonstrating occasional bouts of clonal propagation in an otherwise recombining species. In this model, occasional clonality generates linkage dise...
Long pentraxin 3 (PTX3) is a non-redundant component of the humoral arm of innate immunity. The present study was designed to investigate the interaction of PTX3 with Neisseria meningitidis. PTX3 bound acapsular meningococcus, Neisseria-derived outer membrane vesicles (OMV) and 3 selected meningococcal antigens (GNA0667, GNA1030 and GNA2091). PTX3-recognized microbial moieties are conserved str...
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