Various forms of trophoblastic diseases were reported in the literature, including complete and partial hydatidiform moles, gestational choriocarcinomas, placental-site epitheloid tumors. Among patients who suffer from mole, neoplasia can be easily diagnosed by using levels human chorionic gonadotropin (hCG). Therefore, complex investigations are not usually necessary measuring hCG, physical ex...

Published in 2009, the 7th edition of the American Joint Committee on Cancer TNM staging system is the culmination of an extensive worldwide initiative to standardize and validate lung cancer staging. Unlike prior editions, the new staging system is now inclusive of small cell carcinoma and carcinoid tumors. In addition, significant changes were made to the T and M descriptors, resulting in imp...

Staging systems aim to describe malignant tumours in a standardized fashion to assist in therapy planning and estimation of prognosis, allow comparison of different therapeutic strategies, facilitate communication between individuals and institutions, improve our knowledge of malignant disease and ultimately improve the outcome for patients. With the continuous increase in data and, ideally, ou...

The preoperative prognostic nutritional index (PNI) may forecast colorectal cancer (CRC) outcomes, but the evidence is not conclusive. Here, we retrospectively analyzed a cohort of patients from the Department of Surgical Oncology at the First Hospital of China Medical University (CMU-SO). We also conducted a meta-analysis of eleven cohort studies. Bayesian Information Criterion (BIC) was used ...

There is no consensus on predicting prognosis for hepatocellular carcinoma patients undergoing radiotherapy. This study aims to evaluate the validity of different staging systems. Overall, 249 hepatocellular carcinoma patients were evaluated retrospectively. All patients were classified by different staging systems. The cumulative survival rates were calculated using the Kaplan-Meier method, an...

Esophageal cancer is a disease that has high mortality rate, and its main symptom dysphagia, potentially requiring stent placement. The performance of this patients usually poor we aim study to analyze the survival who underwent placement chemotherapy. An integrative literature review in National Library Medicine Cochrane databases was performed, using descriptors “esophageal cancer” or neoplas...

The anatomic disease extent or tumour stage of a cancer at diagnosis as a determinant of prognosis is discussed. The importance of cancer stage in individual patient prognosis and determination of treatment is reviewed as well as its value in research and cancer control activities. The conflict between the need for stability of cancer stage definitions over time and the need to evolve with adva...

OBJECTIVE To examine the differences in the interval between diagnosis and initiation of treatment among women with breast cancer in Northern Ireland. DESIGN A cross-sectional observational study. SETTING All breast cancer care patients in the Northern Ireland Cancer Registry in 2006. PARTICIPANTS All women diagnosed and treated for breast cancer in Northern Ireland in 2006. MAIN OUTCOM...

It is still difficult to gauge the probability that a patient with low-risk prostate cancer may be upgraded to a higher prostate cancer stage. Upgrading, using the Gleason score after a biopsy, can occur in anywhere from 30% to 50% of prostate cancer cases. Low-risk disease is generally associated with low prostate-specific antigen (PSA) production and a Gleason score of 6 or lower. The Gleason...