نتایج جستجو برای: neoplastic cell
تعداد نتایج: 1695128 فیلتر نتایج به سال:
The progression of normal Syrian hamster embryo cells to a neoplastic phenotype after treatment with a chemical carcinogen and continuous exposure to phorbol ester tumor promoters was studied in cell culture. Tumor promoters were able to rescue cell lines derived from individual carcinogen-treated colonies from a program of cellular senescence. In general, these cell lines did not grow in soft-...
The possibility that neoplastic transformation may characteristically alter cell surface morphology prompted a comparison by scanning electron microscopy of nonneoplastic and tumorigenic cell lines from a single clone of mouse embryo cells. Among those studied by scanning electron microscopy, six lines of this clone proved nonneoplastic, and nine others underwent neoplastic transformation in cu...
A 10-year-old female sea otter exhibited convulsions, arrhythmia, hyperthermia, forced breathing and anorexia and died after a week. Histopathological examination revealed neoplastic proliferation of small round cells with scant cytoplasm and round or oval nuclei distributed mainly in the thalamus. The proliferation of neoplastic cells was observed in the cerebral parenchyma and perivascular ar...
A spontaneous transformant derived from a mouse lung epithelial cell line exhibited decreased cAMP-dependent protein kinase (PKA) activity. DEAE column chromatography demonstrated that this was caused by specific loss of the type I PKA isozyme (PKA I). Western immunoblot analysis indicated that indeed several mouse lung tumor-derived cell lines and spontaneous transformants of immortalized, non...
Attempts were made to transplant neoplastic and non-neoplastic cell lines from tissue culture to animals. The subcutaneous space of hamsters and mice conditioned with x-radiation and cortisone as well as the brains and eyes of normal, unconditioned guinea pigs were used as transplantation sites. No growth of non-neoplastic cell lines was obtained in any site. Neoplastic cell lines grew poorly t...
In a retrospective study, type, origin and relative frequency of pelvic masses during 3 years period in shariati hospital were studied. Ovarian mass was the most common pelvic mass with relative frequency of 88% including neoplastic 58% and non neoplastic 30%. Corpus luteom cyst was the most common cyst in non neoplastic group and serous cystadenoma was the most common in neoplastic group. The ...
BACKGROUND In advanced systemic mastocytosis the response of neoplastic mast cells to conventional drugs is poor and the prognosis is bad. Current research is, therefore, attempting to identify novel drug targets in neoplastic mast cells. Polo-like kinase-1 is a serine/threonine kinase that plays an essential role in mitosis and has recently been introduced as a new target in myeloid leukemias ...
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