The generic classification of the ant subfamily Dorylinae is revised, with the aim of facilitating identification of easily-diagnosable monophyletic genera. The new classification is based on recent molecular phylogenetic evidence and a critical reappraisal of doryline morphology. New keys and diagnoses based on workers and males are provided, along with reviews of natural history and phylogene...

Alpha-synuclein (α-Syn) aggregates are the main component of Lewy bodies, which are the characteristic pathological feature in Parkinson's disease (PD) brain. Evidence that α-Syn aggregation can be propagated between neurones has led to the suggestion that this mechanism is responsible for the stepwise progression of PD pathology. Decreasing α-Syn expression is predicted to attenuate this proce...

The proposal in this document is Experimental. While it may be deployed in the current Internet, it does not represent a consensus that this is the best possible mechanism for the use of Explicit Congestion Notification (ECN) in TCP SYN/ACK packets. This document describes an optional, experimental modification to RFC 3168 to allow TCP SYN/ACK packets to be ECN-Capable. For TCP, RFC 3168 specif...

Parkinson’s disease (PD) is a movement disorder characterized by the appearance of inclusions known as Lewy bodies, most prominently in the substantia nigra pars compacta. The synaptic protein α-synuclein (α-syn) and polyubiquitin are major components of Lewy bodies. The objective of this study was, firstly, to evaluate whether α-syn inhibits proteolytic function of the proteasome and, secondly...

Synucleins (Syn), a family of synaptic proteins, includes alpha-Syn, which plays a pivotal role in Parkinson's disease and related neurodegenerative diseases (synucleinopathies) by forming distinct brain pathologies (Lewy bodies and neurites). Since traumatic brain injury (TBI) is a poorly understood risk factor for Parkinson's disease, we examined the effects of TBI in the young and aged mouse...

This draft specifies a modification to RFC 3168 to allow TCP SYN/ACK packets to be ECN-Capable. For TCP, RFC 3168 only specifies setting an ECN-Capable codepoint on data packets, and not on SYN and SYN/ACK packets. However, because of the high cost to the TCP transfer of having a SYN/ACK packet dropped, with the resulting retransmit timeout, this document specifies the use of ECN for the SYN/AC...

Crematogaster ants are diverse, widespread and abundant in tropical, subtropical and warm-temperate climates throughout the world. The species diversity of this genus has been notoriously difficult to manage based upon morphology alone, and former attempts have generated a vaguely defined subgeneric system. I propose an improvement of the previous subgeneric classification and recognize two sub...

Human nephrotic syndrome has been related to mutations in glomerular proteins. Mutations in the NPHS2 gene that encodes podocin have been described as responsible for steroid-resistant nephrotic syndrome. It has been advised to test for NPHS2 mutations in parallel or before giving steroid treatment in nephrotic syndrome patients in order to avoid unnecessary therapy. We identified NPHS2 mutatio...

Nine 5-bromodeoxyuridine-induced temperature-sensitive (ts) mutants were isolated from stocks of a syncytial plaque type mutant (syn) itself derived from the non-syncytial wild-type (syn +) of the GLASGOW strain i7 of herpes simplex virus type i. The nine ts mutants have been assigned to eight cistrons on the basis of different complementation tests. Non-syncytial revertants isolated from the o...

BACKGROUND Venous thrombosis is common in nephrotic syndrome, but portal vein thrombosis has a relatively low incidence in patients with nephrotic syndrome. We describe here a case of an 18-year old male student with newly diagnosed nephrotic syndrome that was complicated with portal, splenic and superior mesenteric vein thrombosis. CONCLUSION In the presence of newly diagnosed nephrotic synd...