Nerve growth factor (NGF) is a neurotrophin with many functions. In humans, it involved in inflammation, nerve growth, apoptosis and pain signalling. Increased concentrations of NGF synovial fluid has been shown humans dogs osteoarthritis. Despite osteoarthritis being common problem horses, no studies have previously published on the equine joint. The aim this study was to quantify from healthy...

(125)I-Labeled nerve growth factor binds to membrane preparations from superior cervical ganglia of rabbit in a specific fashion indicative of an interaction with the physiological receptor. Of various tissues examined, binding was observed only in the superior cervical ganglia, a presumed target organ of nerve growth factor. Binding of labeled factor is displaced by nonradioactive factor but n...