نتایج جستجو برای: neural cell adhesion molecules

تعداد نتایج: 2098563  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Nicolás Marichal Gabriela García Milka Radmilovich Omar Trujillo-Cenóz Raúl E Russo

The region that surrounds the central canal of the spinal cord derives from the neural tube and retains a substantial degree of plasticity. In turtles, this region is a neurogenic niche where newborn neurons coexist with precursors, a fact that may be related with the endogenous repair capabilities of low vertebrates. Immunohistochemical evidence suggests that the ependyma of the mammalian spin...

Journal: :The International journal of developmental biology 2004
Peter Friedl Yael Hegerfeldt Miriam Tusch

The movement of cells that maintain cell-cell junctions yet protrude along or within tissues is an important mechanism for cell positioning in morphogenesis, tissue repair and cancer. Collective cell migration shares similarities but also important differences to individually migrating cells. Coherent groups of cells are arranged and held together by cell-cell adhesion molecules, including cadh...

2010
Shizhong Li Elisabeth Bock Vladimir Berezin

Fibroblast growth factor receptors (FGFRs) interact with their cognate ligands, FGFs, and with a number of cell adhesion molecules (CAMs), such as the neural cell adhesion molecule (NCAM), mediating a wide range of events during the development and maintenance of the nervous system. Determination of protein structure, in silico modeling and biological studies have recently resulted in the ident...

Journal: :Frontiers in bioscience : a journal and virtual library 2003
Udo Bartsch

Myelination of axons is a prerequisite for the rapid propagation of nerve impulses, and thus for the proper functioning of the nervous system. Phenotypic analysis of genetically engineered mice has provided evidence that cell adhesion molecules are critically involved in the interaction of myelin-forming glial cells with axons, the formation of regularly spaced myelin internodes along axons and...

Journal: :Biophysical journal 2012
E Martines J Zhong J Muzard A C Lee B B Akhremitchev D M Suter G U Lee

Aplysia californica neurons comprise a powerful model system for quantitative analysis of cellular and biophysical properties that are essential for neuronal development and function. The Aplysia cell adhesion molecule (apCAM), a member of the immunoglobulin superfamily of cell adhesion molecules, is present in the growth cone plasma membrane and involved in neurite growth, synapse formation, a...

Journal: :Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 1999

Journal: :The Journal of biological chemistry 1998
S D Storms U Rutishauser

The neural cell adhesion molecule (NCAM) is known to participate in both homophilic and heterophilic binding, the latter including mechanisms that involve interaction with proteoglycans. The polysialic acid (PSA) moiety of NCAM can serve as a negative regulator of homophilic binding, but indirect evidence has suggested that PSA can also be involved in heterophilic binding. We have examined this...

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