Background: Carpal tunnel syndrome is the most common neuropathy in the general population. Nerve conduction studies are among the standard methods for diagnosing carpal tunnel syndrome. Electromyography is painful and unpleasant, and if nerve conduction studies can be used to diagnose axonal injury in carpal tunnel syndrome, electromyography might be replaced. Objectives: This study aimed t...

In the developing nervous system of Drosophila, cells in each proneural cluster choose between neural and epidermal cell fates. The neurogenic genes mediate the cell-cell communication process whereby one cell adopts the neural cell fate and prevents other cells in the cluster from becoming neural. In the absence of neurogenic gene function, most, if not all of the cells become neural. big brai...

PURPOSE Examine a contemporary series of patients with primary pediatric malignant mediastinal tumors and determine epidemiology, histology, treatment, and survival. Patients and Methods. All malignancies diagnosed between January 1, 1973 and December 31, 1995 were analyzed. RESULTS Twenty-two patients, age 18 years or less, with pediatric primary mediastinal malignancies were identified from...

A Chiari malformation Type I may remain asymptomatic until the patient has reached adulthood and acute presentation of symptoms occurs. In several clinical and experimental studies it has been shown that essential hypertension is associated with vascular compression of the brainstem, particularly of the rostral ventrolateral medulla oblongata. Nevertheless, two cases of Chiari malformation and ...

Neurogenic Control of Cerebral Circulation • A review of recent literature provides evidence that cerebral vessels are innervated with myelinated and nonmyelinated nerves. Among the latter, adrenergic nerves are readily demonstrated. Stimulation of cervical sympathetics produces a reduction in cerebral blood flow attributable to constriction of vessels in the neck and on the cerebral surface. I...

Objectives: To review the up-to-date literature of the mostly used conservative treatment modalities in patients with neurogenic bladder. Methods: material from literature on conservative management in patients with neurogenic bladder was reviewed. Pubmed search results and recent books were consulted. Results: The conservative treatment is in almost all cases the first and will remain the prim...

Neuronal precursors (neuroblasts) of the Drosophila embryo delaminate from a specialized ectodermal territory called neurogenic region. A group of genes, called neurogenic genes, were shown to control the balance between those cells of the neurogenic region that delaminate as neuroblasts and those that stay behind as epidermal precursors (Lehmann et al., 1983). Thus, embryos lacking the functio...

'Neurogenic thoracic outlet syndrome' is a poorly defined and controversial term for a group ofupper extremity nerve compression disorders.' The objective of this article is to summarize current knowledge, review controversies, and formulate a rational management plan for neurogenic thoracic outlet syndromes (NTOS). We will present a balanced perspective that considers thoracic surgical and neu...

In search for drugs to treat neuropsychiatric disorders wherein neurotrophic and neurogenic properties are affected, two neurotrophically active small molecules specially crafted following natural product leads based on 2-oxa-spiro[5.5]-undecane scaffold, have been thoroughly evaluated for their neurotrophic, neurogenic and neuroprotective potential in ex vivo primary culture and in vivo zebraf...

During neocortical development, neural precursor cells (NPCs, or neural stem cells) produce neurons first and astrocytes later. Although the timing of the fate switch from neurogenic to astrogenic is critical for determining the number of neurons, the mechanisms are not fully understood. Here, we show that the polycomb group complex (PcG) restricts neurogenic competence of NPCs and promotes the...