Antiphospholipid antibodies (aPL) have been most strongly associated with a syndrome (APS) characterized by venous and/or arterial thrombosis, thrombocytopenia, recurrent fetal losses and a variety of non-thrombotic and thrombotic neurological disorders. Cerebral ischemia associated with aPL is the most common arterial thrombotic manifestation. Other neurological syndromes, such as cognitive dy...

Chemotherapy-induced peripheral neuropathy (CIPN) is a well-documented toxicity leading to dose limitation. Ibrutinib an oral Bruton’s Tyrosine Kinase (BTK) inhibitor approved for treating chronic lymphocytic lymphoma. The most common neurological side effects of include headache and dizziness. Herein, we report as dose-limiting manifestation treatment.

The neurological evaluation of infants and children differs from that of older children and adults principally because of the phenomenon of development. The process of development alters the neurological behaviors and functions that would be expected at different ages. Development also changes the findings on physical examination. Finally, the natural history and manifestation of abnormal funct...

The most common neurological manifestation of Cryptococcus neoformans infection is meningitis. Other less common manifestations include parenchymal central nervous system (CNS) granulomatous disease, hydrocephalus and stroke. C. neoformans is often suspected in immunodepressed patients, but it can be easily overlooked in otherwise healthy patients. This paper provides a detailed clinical descri...

Metastasis of kidney cancer to the bone tissue can be manifested through development pathological fractures and spinal cord lesions. The clinical case clear cell renal carcinoma with solitary metastasis in thoracic spine presented this article demonstrates possibility manifestation disease neurological symptoms importance timely comprehensive diagnosis adherence treatment deadlines.