and genetic basis of various neuromuscular, demyelinating and neu-ronal disorders affecting muscle, nerves, or brain, and applying new therapeutic interventions via target-oriented control therapeutic clinical trials. He is the author or coauthor of more than 500 scientific papers or chapters in peer-reviewed journals. He has also edited 11 books and monographs and currently serves on the edito...

Neuromuscular disorders constitute a significant proportion of neurologic complaints. However, it has not been very long since they came into focus in Iran. The first specialized meeting on muscle and nerve disorders was held in Isfahan, 2010. The second gathering took place soon after in Tehran 2011 as a joint program with French experts.1 Kerman was the third place to contribute to neuromuscu...

The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) developed guidelines to formalize the ethical standards that neuromuscular and electrodiagnostic (EDx) physicians should observe in their clinical and scientific activities. Neuromuscular and EDx medicine is a subspecialty of medicine that focuses on evaluation, diagnosis, and comprehensive medical management, includ...

UNLABELLED Neuromuscular diseases represent an important group in pediatric pathology. Immunohistochemistry together with clinical examination and morphologic exam are very important in the diagnosis of neuromuscular disorders. PATIENTS AND METHODS One hundred children diagnosed with neuromuscular disorders were included in a prospective-retrospective study in 25 years. RESULTS There were 5...

Neuromuscular disorders are known to be associated with cardiac disease but often the cardiovascular symptoms can be difficult to unravel due to low physical activity in this patient group and thereby low strain on the heart. On the other hand, cardiomyopathy or cardiac arrhythmogenic disease may be the first sign of an underlying neuromuscular disorder. Indeed, of the more than 40 genes that h...

OBJECTIVE To show that immunotherapy with medications such mycophenolate mofetil (MMF) can cause serious complications in patients with neuromuscular disorders. METHODS Two patients with neuromuscular disorders on immunotherapy with long-term MMF who developed toxoplasmic encephalitis (TE) were included in this case series. RESULTS One patient with myasthenia gravis and one patient with inf...

BACKGROUND Children with neuromuscular disorders with a progressive muscle weakness such as Duchenne Muscular Dystrophy and Spinal Muscular Atrophy frequently develop a progressive scoliosis. A severe scoliosis compromises respiratory function and makes sitting more difficult. Spinal surgery is considered the primary treatment option for correcting severe scoliosis in neuromuscular disorders. S...

An understanding of the possible causes, prevention and treatment of rare, so-called 'orphan disease' requires collaboration in research between different centres with the sharing of information. In the case of neuromuscular disorders (such as muscular dystrophies or hereditary neuropathies) this has been achieved through European collaborative research encouraged and facilitated by the Europea...