نتایج جستجو برای: neurosphere
تعداد نتایج: 653 فیلتر نتایج به سال:
The molecular mechanisms of prion-induced cytotoxicity remain largely obscure. Currently, only a few cell culture models have exhibited the cytopathic changes associated with prion infection. In this study, we introduced a cell culture model based on differentiated neurosphere cultures isolated from the brains of neonatal prion protein (PrP)-null mice and transgenic mice expressing murine PrP (...
Circadian rhythms are common in many cell types but are reported to be lacking in embryonic stem cells. Recent studies have described possible interactions between the molecular mechanism of circadian clocks and the signaling pathways that regulate stem cell differentiation. Circadian rhythms have not been examined well in neural stem cells and progenitor cells that produce new neurons and glia...
T he exquisite sensitivity of the human ear to sound depends on the proper function of mechanosensory hair cells that transduce mechanical stimuli into electrical signals. Sound-induced deflections of bundles of actin-rich microvilli that protrude from the apical surface of hair cells evoke changes in the open probability of nonselective ion channels that modulate cellular excitability and syna...
Testosterone-induced adult neurosphere growth is mediated by sexually-dimorphic aromatase expression
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