Abstract Phosphopenic rickets may be caused by mutations in the PHEX gene (phosphate regulating endopeptidase homolog X-linked). Presently, more than 500 have been found to cause hypophosphatemic rickets. The authors report a clinical case of 4-year-old girl with unremarkable family history, who presented failure thrive and bowing legs. Laboratory tests showed hypophosphatemia, elevated alkalin...

conclusions these data will be beneficial for designing more advanced antibodies for the recognition of the hbsag in diagnostics. in addition, the results of this study may assist in the design or development of more effective hepatitis b vaccines. results the g145r mutation causes a considerable reduction in the immunogenic activity of the hbsag through a conformational change in the hbsag ant...

Abstract A 62–year–old man diagnosed with non–obstructive hypertrophic cardiomyopathy and dual–chamber pacemaker wearer since the age of 40, for third–degree atrioventricular block, came to our attention atrial fibrillation (AF) episodes (one complicated by cardiogenic shock multiorgan failure) flutter high ventricular response. For a progressive worsening systolic function, onset multiple sust...