1 Enhorning C, Robertson B. Lung expansion in the premature rabbit fetus after tracheal deposition of surfactant. Pediatrics 1972; 50:58-66 2 Ikegami M, Agata Y, Elkady T, Hallman M, Berry D, Jobe A. Comparison of four surfactants: in vitro surface properties and responses of preterm lambs to treatment at birth. Pediatrics 1987; 79:38-46 3 Cummings JJ, Hoim BA, Hudak ML, Hudak BB, Ferguson WH, ...

This investigation is part of a comprehensive effort to determine the degree of vagal function in newborn infants. No particular attention has been given to this problem previously, but in the light of recent experimental work in animals there is a clear indication for such a survey in newborn infants. The presence of an effective vagal mechanism is essential to the life of newborn kittens and ...

Pulmonary artery pressure may be estimated non-invasively in the premature newborn infant because of its negative correlation with the time to peak velocity:right ventricular ejection time (TPV:RVET) ratio calculated from the pulmonary artery Doppler waveform. We studied 54 very low birthweight infants on days 1, 2, 3, 7, 14, 21, and 28 after birth. Thirty four infants developed chronic lung di...

Holt-Oram syndrome is an autosomal dominant condition characterized by skeletal and cardiac defects. Pulmonary malformation is not reported to belong to the spectrum of this condition. We report a second case of a newborn with Holt-Oram syndrome who developed severe respiratory insufficiency shortly after birth. We discuss possible genetic links between abnormal pulmonary morphogenesis and Holt...

OBJECTIVE Exploring maternal experience with premature newborn children in a domestic environment. METHODS The study was qualitative and used focus group interviews with 24 women who had had preterm deliveries in a public maternity hospital located in Northeast Brazil during June and October 2005. The mothers returned to the hospital facility at least 30 days after the newborn were discharged...

background: metabolic bone diseases (mbd), including rickets and osteopenia, are important neonatal complications among preterm infants. this study aimed to determine the prevalence and risk factors of mbd in neonates with very low birth weight (vlbw). methods: this prospective study was conducted on vlbw infants from january 2012 to july 2013. inclusion criteria were birth weight of ≤1500 g an...

various statistical methods have been proposed in terms of predicting the outcomes of facing special factors. in the classical approaches,  making the probability distribution or known probability density functions is ordinarily necessary to predict the desired outcome. however, most of the times enough information about the probability distribution of studied variables is not available to the ...

background: preterm birth is the major cause of neonatal mortality and morbidity. objective: the aim of this study was to evaluate the effect of prophylactic vaginal progesterone on decreasing preterm birth rate and neonatal complications in a high-risk population. materials and methods: a randomized, double-blind, placebo-controlled study was performed on 100 high-risk singleton pregnancies. v...

OBJECTIVE To test the hypothesis that prophylactic treatment with the surfactant Curosurf (Chiesi Farmaceutici SPA, Parma, Italy) improves survival and respiratory problems more than rescue treatment. DESIGN Meta-analysis of three prophylaxis versus rescue treatment trials, conducted in four countries. METHODS A meta-analysis was performed with the original, individual data of mortality, se...

INTRODUCTION Respiratory syncytial virus is a common neonatal pathogen. Here we present a case of a premature, low birth weight infant who contracted respiratory syncytial virus and developed a severe pulmonary hemorrhage. CASE PRESENTATION A 12-day-old Asian male, former 30 week premature infant with a birth weight of 1025 grams presented with nasal secretions, episodes of desaturations and ...