p53 over expression in yeast results in cell death with typical markers of apoptosis such as DNA fragmentation and phosphatidylserine externalization. We aimed to substitute/supplement classical fluorescent techniques (TUNEL, Annexin V, ROS detection) usually used to detect biochemical changes occurring during yeast apoptosis mediated by p53 over expression and the effect of anti-apoptotic puri...

In this paper a class of closed queueing network is modelled in the Markovian process algebra PEPA. It is shown that a fluid flow approximation using ordinary differential equations (ODEs) gives rise to well known asymptotic results. This result gives context to the use of a fluid flow approximation and is potentially useful in cases where the model is not obviously a closed queueing network. T...

Why did you choose the profession of scientific investigation? Ever since I was a kid, I was fascinated in how things worked. I loved being outdoors interacting with nature. Biology was my best subject at school, and I found it really easy compared with other subjects―it all made sense. When I was 12, I decided I would get a PhD and become a scientist. For some reason my school advisor tried to...

A century and a half after the ground-breaking work by Gregor Mendel in establishing the foundation of genetics, efforts are under way to develop a fitting commemoration of his work at his abbey home in Brno. Nigel Williams reports.

Orchids show an astonishing floral diversity yet an ability to hybridize in the hands of breeders. Nigel Williams reports on a new study that shows how neighbours appear to avoid the hybrid trap in the wild.

Compassionate love has received research attention over the last decade, but it is as yet unclear how it is experienced over a lifetime. The purpose of this study was to investigate compassionate love for a romantic partner throughout the adult life span, exploring individual differences in the propensity to experience compassionate love in regard to age, gender, religion, love status, love sty...