OBJECTIVES This study was undertaken to investigate the protective effects of vitamin B6, cofactor for cystathionine-γ lyase and cystathionine-β synthase (producers of H2S), alone and in combination with L-cysteine, H2S precursor, on indomethacin-, and ethanol-induced gastric lesions in male NMRI mice. MATERIALS AND METHODS Fasted male NMRI mice were randomly assigned into 12 groups (7 in eac...

Nuclear magnetic resonance (NMR) is a recent addition to the imaging techniques available to the neonatologist evaluating disease in the newborn. Reports of this new modality are at present few and the role for NMR imaging (NMRI) is not yet clear but we have encouraging indications of the direction that further research may pursue. The aim of this review article is to consider the potential adv...

Ficoll-purified lymphocytes (peritoneal, splenic, or thymic) and macrophages (peritoneal) from Toxoplasma-immune and normal female NMRI mice were used. Suspensions of washed cells were made in medium 199 containing 20% heat-inactivated normal calf serum. Sixty minutes after the adherence of 10(5) macrophages to cover slips in Leighton tubes, lymphocytes were added in various concentrations. The...

BACKGROUND This investigation aimed to evaluate the in vitro scolicidal effects of Pistacia khinjuk methanolic extract against protoscoleces of hydatid cysts and its acute toxicity in mice NMRI model. METHODS Protoscoleces were aseptically extracted from sheep livers having hydatid cysts. Various concentrations of the essential oil (12.5-100 mg/mL) were used for 10 to 60 min. Viability of pro...

BACKGROUND Over the past several years, mammals have been successfully cloned by either the splitting of an early stage embryo or nuclear transfer of adult somatic cells (NT) into oocytes. Although it has been 15 years since the generation of the first cloned mammals from somatic cells by NT, the success rate for producing live offspring by this technique is low regardless of the cell type and ...

Aims: The aim of this study was to evaluate the anti-inflammatory and analgesic activities Daniellia oliveri methanolic extract its fractions in NMRI mice.
 Study Design: In vivo acute toxicity, assays.
 Place Duration Study: work carried out Department Traditional Pharmacopoeia Pharmacy (MEPHATRA / PH) Research Institute for Health Sciences (IRSS) Ouagadougou (Burkina- Faso) between ...

The dependence of spermatogenesis function on murine age shall be investigated. Thus, testicular samples of at least 10 NMRI mice per group aged 0 to 26 months are analysed by flow cytometry after staining the DNA with DAPI. The aim of this study is to be able to account for the influence of age on mice. There are no changes in spermatogenesis in mice aged 11 weeks up to 16 months with respect ...

Objective Mesial temporal lobe epilepsy (TLE) with hippocampal sclerosis is a predominant form of acquired epilepsy, characterized by recurrent simple and complex partial seizures that are often resistant to treatment. Mice developing spontaneous recurrent nonconvulsive and convulsive seizures after intrahippocampal injection of the excitotoxic glutamate agonist kainate are thought to represent...

BACKGROUND Galectin-3 (Gal-3), a β-galactoside-binding lectin, is a multifunctional lectin that involves in a number of critical biological processes. OBJECTIVE The purpose of this study was to investigate the expression pattern of Gal-3 in mouse endometrium during estrus phase of estrous cycle and pre-implantation. MATERIALS AND METHODS In this experimental study 42 NMRI female mice were d...