We report here brain abscesses caused by Nocardia beijingensis in a 59-year-old-Thai male with human immunodeficiency virus (HIV) infection presenting with progressive right sided hemiparesis. A computed tomography scan of the brain showed multiple brain abscesses. A stereotactic brain biopsy and 16S rRNA sequencing showed Nocardia beijingensis. The patient was treated with trimethoprim-sulfame...

Nocardial infection is caused by soil-borne aerobic bacteria. Nocardia in ischiorectal abscess is a rare presentation. Here, we present a case of ischiorectal abscess in an immunocompetent male patient with a history of trauma. The isolate was identified as Nocardia asteroides by standard methods. The patient responded well to amikacin and surgical drainage. Thus, this case highlights the impor...

Nocardiae are Gram-positive, filamentous, aerobic, relatively slow-growing, and weakly acid-fast bacteria which cause nocardiosis in humans. We describe a 53-year-old patient with chronic bronchitis referred to Al-Zahra Hospital, Isfahan. A bronchial washing sample was taken from the patient. A Nocardia-like microorganism was detected in microscopic evaluation. Based on the phenotypic and 16S r...

Nocardia infection occurs primarily among patients with deficient cell-mediated immunity. The portal of entry in the majority of patients with Nocardia infection is pulmonary origin. Central venous catheter-associated bacteremia caused by Nocardia species is very rare, and the optimal management for these situations was indeterminate. Most patients were cured after discontinuation of central ve...

Nocardia is a gram positive, aerobic branched actinomycete; it is an ubiquitous soil saprophyte. As an infecting agent it has been increasingly identified in humans, especially in immuno-suppressed hosts. Nocardia as a cause of septic arthritis is very unusual. The described genus was Nocardia asteroides in nearly all previously reported cases. We report an unusual case of spontaneous Nocardia ...

Recent studies in the Parkinson's literature have cited a tuberculosis-like germ called Nocardia as being responsible for Parkinson's disease. Kohbata seemingly cemented a relationship between Nocardia and Parkinson's by finding serologic evidence in 20 of 20 Parkinson's patients, acknowledging that blood tests for Nocardia and the mycobacteria such as tuberculosis often cross-react, as they be...

Nocardia species are aerobic, gram-positive, filamentous, partially acid-fast actinomycetes which are found worldwide in soil and decaying organic plant matter. When they infect human beings, they generally enter through the respiratory tract and then disseminate systemically. Rarely has a primary infection occurred as the result of direct inoculation. Isolation of Nocardia from clinical specim...

purpose: to report 3 cases of nocardia keratitis following photorefractive keratectomy (prk). report of outbreak: four eyes of 3 patients (2 female and one male) who had undergone prk by a single surgeon at a single center developed nocardia keartitis 3 to 6 weeks postoperatively. mean age was 25 (range 23-28) years and mean onset of corneal manifestations was 29 (range 21-40) days after prk. c...

26 Antimicrobial susceptibility testing (AST) of clinical isolates of Nocardia is recommended to 27 detect resistance to commonly used antimicrobial agents; such testing is complicated by 28 difficulties in inoculum preparation and test interpretation. In this study, six laboratories 29 performed repetitive broth microdilution testing on single strains of Nocardia brasiliensis, 30 Nocardia cyri...

Recent reports of increasing in vitro sulfonamide resistance in Nocardia prompted us to investigate the findings. Despite the reports, there is a paucity of clinical reports of sulfonamide failure in treatment of nocardia disease. We reviewed 552 recent susceptibilities of clinical isolates of Nocardia from six major laboratories in the United States, and only 2% of the isolates were found to h...