9 A pipeline for automatic semantic annotation of human connectomics revealed by diffusion tractography Introduction Predictive modelling of functional connectomes from structural connectomes explores commonalities across multi-modal imaging data [1]. Brain structure not only constrains but also shapes functional connectomes. We exploit this property to devise a statistically sound way, based o...

Optimal myelination of neuronal axons is essential for effective brain and cognitive function. The ratio of the axon diameter to the outer fiber diameter, known as the g-ratio, is a reliable measure to assess axonal myelination and is an important index reflecting the efficiency and maximal conduction velocity of white matter pathways. Although advanced neuroimaging techniques including multico...

We present a novel multi-shell position-orientation adaptive smoothing (msPOAS) method for diffusion weighted magnetic resonance data. Smoothing in voxel and diffusion gradient space is embedded in an iterative adaptive multiscale approach. The adaptive character avoids blurring of the inherent structures and preserves discontinuities. The simultaneous treatment of all q-shells improves the sta...