OBJECTIVE Nodular fasciitis is a benign proliferative spindle-cell lesion found in the subcutaneous fascia that presents as a rapidly growing mass with rich cellularity and mitotic activity, leading to it frequently being mistaken for a sarcoma. Histomorphologic features and immunohistochemical profile are useful in proper diagnosis. The treatment is complete excision, and recurrence is uncommo...

We report the case of a 7-year-old Japanese girl with nodular fasciitis which was investigated by immunohistological and electron microscopical methods. An excised nodular lesion in her right orbit showed characteristic histological features of the disease. The fibroblastic cells showed myofibroblastic characteristics, such as immunohistochemically positive reactions against muscle specific act...

Papillary thyroid carcinoma with nodular fasciitis-like stroma (PTC-NFS) is a rare variant of PTC. The term 'PTC with fibromatosis-like stroma' has been used as a synonym to describe this variant. It is characterized by extensive proliferation of fibroblasts and myofibroblasts in the tumor stroma, which occurs in up to 80% of the tumors. We herein describe a case of PTC-NFS which developed in a...